June 8, 2017August 24, 2022

Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

The MEK inhibitor Mekinist (trametinib) is to be tested in combination with  Opdivo (nivolumab) — or Opdivo plus Yervoy (ipilimumab) — in colorectal cancer patients with microsatellite stable tumors under a clinical collaboration between Novartis ... Read more

June 6, 2017

Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Certain patients who underwent surgery for lymph-node positive colon cancer (stage 3) may require only three months of chemotherapy after surgery instead of the standard six months, according to an analysis ... Read more

June 1, 2017June 1, 2017

Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

The MEK inhibitor binimetinib will soon be tested in combination with Opdivo (nivolumab) plus Yervoy (ipilimumab) in colorectal cancer patients with microsatellite stable tumors, under a clinical collaboration between Array ... Read more

May 30, 2017

PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

Trovagene’s PCM-075 therapy for several blood cancers and solid tumors, including colon cancer, proved safe in a Phase 1 clinical trial. The results of the trail conducted by Nerviano Medical ... Read more

May 25, 2017May 25, 2017

FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Colorectal cancer patients with unresectable or metastatic tumors bearing a genetic feature — microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) — will now have access to Merck‘s immune checkpoint inhibitor Keytruda (pembrolizumab). ... Read more

May 23, 2017

Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Overweight boys have a higher risk of developing colon cancer in adulthood, but if they lose the extra pounds by young adulthood, that higher risk goes away, a Danish study ... Read more

May 18, 2017May 18, 2017

Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Tom Marsilje, who survived stage IV colorectal cancer (CRC), has joined forces with New York-based Fight Colorectal Cancer to help patients search for microsatellite stable (MSS-CRC) clinical trials. The updated tool, now called the ... Read more

May 16, 2017

Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

The Colon Cancer Coalition, a nonprofit organization that encourages grassroots efforts to promote colon cancer awareness and screening, is partnering with Olympus Corporation of the Americas (OCA) to try to ... Read more

May 11, 2017

Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

A new European project aims to develop an innovative endoscope device that can detect and diagnose colorectal cancer in its early stages. Called PICCOLO, the project is funded under the European Union’s Horizon ... Read more

May 9, 2017

Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

People who eat healthy, exercise, and do not smoke are less likely to report a personal history of colorectal cancer or colon polyps, according to a Cleveland Clinic online survey. Another key ... Read more

May 4, 2017May 4, 2017

RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

Small molecule compounds known as RLR agonists, being developed by Kineta to treat colon cancer, were seen to kill cancer cells in a mice model of the disease. Those animals ... Read more

May 2, 2017May 2, 2017

New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research

MIT researchers using the CRISPR-Cas9 genome editing and organoid technology have developed a new mouse model with a cancer that closely resembles colon cancer in humans. This new model may help scientists ... Read more

April 27, 2017

More Than Nine-month Delay Between Feces Test and Colonoscopy Increases Colon Cancer Risk

Failing to get a diagnostic colonoscopy within nine months of a feces test that indicates the possibility of colorectal cancer increases the risk of a person developing the cancer, a Kaiser ... Read more

April 20, 2017April 20, 2017

Colon Cancer Experimental Therapy AMC303 Also Inhibits Pancreatic Tumors in Mice, Study Shows

AMC303 inhibited tumor growth and prevented the spread of colorectal, and other cancer cells, and of a pancreatic cancer in a mouse model, amcure reported at the American Association for Cancer Research’s annual ... Read more

April 18, 2017April 18, 2017

UConn Center Uses More than Colonoscopy to Prevent Colorectal Cancer

While regular colonoscopy remains the gold standard in preventing colorectal cancer, the understanding of how this cancer and the polyps that come before it develop is changing rapidly. Joel Levine, co-founding ... Read more

April 13, 2017

FDA Grants Priority Review to Application Seeking Opdivo’s Approval for Certain Colorectal Cancer Patients

The supplemental Biologics License Application (sBLA) requesting the extension of Opdivo’s indications to include metastatic colorectal cancer patients who have mismatch repair deficiencies (dMMR) or high microsatellite instability (MSI-H), has ... Read more

April 6, 2017

Patient Is Key Factor That Predicts Colorectal Cancer Screening, Study Finds

The term “self-efficacy,” or a patient’s confidence to schedule, plan for, and complete their part in medical screening procedures, was found to be a key determining factor for predicting a ... Read more

April 4, 2017April 4, 2017

Study: Hispanic Colorectal Cancer Patients Live Nearly Twice as Long After Diagnosis as Blacks or Whites

Black and Hispanic colorectal cancer patients have a worse health-related quality of life (HR-QoL) than white patients, yet Hispanics survive an average 85.4 months after diagnosis — nearly twice as ... Read more

March 30, 2017March 30, 2017

Disabled Adults Less Likely to Receive Routine Colorectal Cancer Screening, Study Finds

Americans with impaired vision, intellectual disabilities or spinal cord injuries are less likely to receive recommended colon cancer screenings than the general population, a new study found. The study, “Colorectal Cancer ... Read more

March 29, 2017

Biobank Can Help Colon Cancer Patients Manage Their Disease Better

One way for those with colorectal cancer to become more involved in the management and treatment of their disease is to check out the Penn State Colorectal Diseases Biobank. “For ... Read more

March 23, 2017March 23, 2017

Gut Bacteria Explains Increased Colon Cancer Risk in African-Americans

The higher intake of animal fat and meat among African-Americans is a potential environmental risk factor for colorectal cancer, as it changes to composition of their gut microbiota, according to results ... Read more

March 21, 2017March 21, 2017

Enhancer DNA Regions May Promote Colon Cancer Growth

Colon cancer growth may be dependent on increased activity in enhancer DNA regions, which act to trigger the harmful actions of known cancer genes, according to a study that explored ... Read more

March 16, 2017March 16, 2017

Quantifying Immune Cells in Colon Tumors May Identify Cancer Patients at High Risk of Recurrence

The presence of immune cells within tumors can predict how well cancer patients are likely to fare, according to a recent study. Researchers at New Zealand’s University of Otagov found that ... Read more

March 14, 2017

Healthy Lifestyle Overrides Genetic Risk Factors of Colon Cancer

Lifestyle factors play a much larger role than genetic risk in determining who gets colon and rectal cancer, according to a study that modeled cancer risk using both lifestyle and ... Read more

March 9, 2017

CBT Presents Positive Preclinical Data for CBT-501 Colon Cancer Therapy

The anti-PD-1 antibody CBT-501 (genolimzumab) may offer hope to colon cancer patients, according to preclinical data recently presented by CBT Pharmaceuticals, a life sciences oncology company based in Santa Clara, California. During the ... Read more

March 7, 2017

Colorectal Cancer Rates Rising in Adults Younger Than 50, Statistics Show

While colorectal cancer incidence and mortality rates have seen significant reductions since 2000 in older people, these numbers seem to be increasing in adults younger than 50, according to the ... Read more

March 2, 2017March 2, 2017

Cancer Death Rates to Fall Faster in European Men than Women in 2017, Scientists Predict

The death rate of European men with cancer will fall faster than in women this year, according to predictions based on data about cancer patterns. Researchers, who have been doing ... Read more

February 28, 2017

Mologen’s DNA-based Immunotherapy Shows Promise in Preclinical Colon Cancer Models

Combining Mologen’s TLR9 agonists EnanDIM with an anti-PD-1 immune checkpoint inhibitor may be a promising approach to treat colon cancer patients. The preclinical data was presented at the 2017 Clinical Immuno-Oncology Symposium ... Read more

February 23, 2017

Inherited Mutations Linked to Colorectal Cancer More Frequent than Believed, Study Finds

The likelihood of having an inherited gene mutation linked to colorectal cancer may be higher than previously believed, according to researchers from the Dana-Farber Cancer Institute. In a study of ... Read more

February 21, 2017

Two New Biomarkers May Help Predict Colorectal Cancer Patients’ Response to Therapy

Researchers identified two biomarkers that predict whether patients with colorectal carcinoma will respond well to treatment with Erbitux (cetuximab) or the chemotherapy agent 5FU, according to a new study. These ... Read more

February 16, 2017February 16, 2017

Researchers Develop Potential Antibody to Battle Colon, Other Cancers

Researchers have developed a new antibody approach that may help fight a broad range of cancers, including colon cancer, according to a new study. The antibody targets the SIRPα protein, ... Read more

February 14, 2017

Study Shows Link Between Smoking, Higher Death Risk for Colon Cancer Patients Undergoing Surgery

Colon cancer patients who smoked at the time of diagnosis were more likely to die of cancer within five years than patients who never smoked, according to the results of ... Read more

February 9, 2017February 9, 2017

Eating Nuts Regularly May Lower Risk of Colon Cancer, Study Suggests

People who consume nuts every day may be less likely to develop colon cancer, findings from a recent German study suggest. The team has found that nuts — including almonds, hazelnuts, macadamia ... Read more

February 7, 2017

Low-fat, High-fiber Diet Cuts Risk of Bacteria-linked Colon Cancer, Study Says

A diet rich in whole grains and fiber may protect against colon cancer by reducing the amount of a bacteria in the intestine that is thought to contribute to the onset ... Read more

February 2, 2017

Young, Middle-aged Colon Cancer Patients More Apt to Receive Post-Surgery Chemotherapy

Young and middle-aged colon cancer patients are two to eight times more likely to receive adjuvant chemotherapy (given after surgery) than older patients, researchers have found. But evidence also shows ... Read more

January 31, 2017

New Biomarker Could Improve Treatments for Colorectal Cancer with Liver Metastasis

The protein VEGF-A, which is involved in the formation of new blood vessels, often predicts poor prognosis when found in primary tumors. But researchers have now revealed that that may ... Read more

January 26, 2017

CaroGen and University of Connecticut Collaborate to Develop Colon Cancer Vaccine

The University of Connecticut and the immunotherapy company CaroGen are collaborating to develop a new vaccine to treat colon cancer patients. The vaccine will use CaroGen’s proprietary technology platform, which relies ... Read more

January 24, 2017

Colon Cancer Diagnoses Increased 8% Under Affordable Care Act, Study Shows

The Affordable Care Act (ACA) was found to be effective in making recommended colorectal cancer screening more affordable and accessible for millions of Americans, according to a new study. The ... Read more

January 19, 2017

‘Collateral Lethality’ Offers New Therapeutic Target for Colon, Other Cancers

During the transformation of cells into a malignant cancerous form, some tumor suppressor genes that are responsible for blocking this process are deleted. At times, this genomic editing process can also ... Read more

January 17, 2017

Colorectal Cancer Cells Able to Use Glutamine to Survive, Study Finds

Tumor cells usually rely on glucose to grow, but some are known to change their metabolism to survive in stressful environmental conditions. Researchers have discovered that is true in colorectal cancer, ... Read more

January 12, 2017

Asana Initiates Phase 1 Trial of New Therapy for Colorectal, Other Solid Tumors

Asana BioSciences is enrolling participants for a Phase 1 clinical trial assessing the safety, tolerability, and effectiveness of AS003 in patients with advanced solid tumors with the BRAF V600 mutation or with ... Read more

January 10, 2017

MMP9 Protein May Protect Against Inflammation-Derived Colon Cancer

An inflammatory protein called MMP9 may protect against the development of colitis-associated cancer (CAC), a type of colorectal cancer associated with chronic inflammatory diseases, a new study says. The study, ... Read more

January 5, 2017

Phase 1b Study of Combo Therapy for Metastatic Colorectal Cancer Begins Dosing

OncoMed Pharmaceuticals announced the dosing of the first patient in a Phase 1b clinical study evaluating the combination of its anti-DLL4 /VEGF bispecific antibody (OMP-305B83) and chemotherapy in people with second-line metastatic colorectal cancer ... Read more

January 3, 2017

Sensor Protein Seen to Protect Against Colon Cancer Development

Results from a new study suggest that a sensor protein called NLRC3 could play an important role in preventing the development of colon cancer. The study, “NLRC3 Is An Inhibitory Sensor ... Read more

December 22, 2016

Multi-Gene Screening Essential for Early Onset Colorectal Cancer Patients, Study Advises

Sixteen percent of colorectal cancer patients diagnosed before they are 50 years old have at least one inherited genetic mutation that increases their risk of developing the disease, according to ... Read more

December 20, 2016

Aspirin Slows Colon, Pancreatic Cancer Growth by Inhibiting Platelets, Study Shows

Aspirin may help slow the growth of localized colon and pancreatic cancers by inhibiting the cross-talk between cancer cells and platelets, according to research published in the American Journal of Physiology – ... Read more

December 15, 2016December 15, 2016

Notch Signaling Inhibitor Shows Promise as Treatment for Colon, Other Cancers, Study Shows

A new treatment for colon and other cancers that addresses mutations of the Notch signaling pathway is showing promise, researchers say. “Notch signalling is an important contributor to the development of ... Read more

December 13, 2016

Vaccine Being Developed May Help Prevent Colon Cancer Metastasis

Scientists at Thomas Jefferson University’s Sidney Kimmel Medical College in Philadelphia have developed an innovative new vaccine designed to halt the spread (metastases) of gastrointestinal tract cancers. These include malignancies ... Read more

December 6, 2016December 6, 2016

Diagnostic Agent Detects Colorectal Cancer Response to Therapy in 1 Day in Mice

A preclinical study showed that response of colorectal cancer to treatment can be detected after a single administration using the diagnostic agent TumorVue (99mTc-duramycin), developed by Molecular Targeting Technologies (MTTI). These ... Read more

December 1, 2016December 1, 2016

Synthetic Protein May Work as RAS Inhibitor to Treat Colon and Other Cancers

Nearly 30 percent of all cancers have activating mutations in the RAS family of proteins, but researchers have struggled to safely block these tumor-promoting proteins. But an approach taken by a team at University ... Read more

November 29, 2016November 29, 2016

Fine Line Seen Between Colon Cancer Suppression and Gut Renewal in Study

The gut has a remarkable capacity for regeneration after chemotherapy or radiation, thanks to a type of reserve stem cell. But while activating these cells could help patients heal after cancer treatment, ... Read more

November 22, 2016

European Clinicians Question Latest US Colorectal Cancer Screening Guidelines

Earlier this year, the U.S. Preventive Services Task Force (USPSTF) updated the recommendations for colorectal cancer screening. But European clinicians claim that USPSTF recommendations lack strength and quality of evidence. ... Read more

November 17, 2016

Left-sided Colon Cancer Associated with Better Prognosis than Right-sided, Study Finds

The side of origin of colon cancer has been associated with distinct genetic profiles and clinical presentations. Researchers have now shown that this impacts patients’ prognosis, with left-sided colon cancer associated ... Read more

November 15, 2016

Weight Loss After Obesity Fails to Protect Mice from Colon, and Possibly Liver, Cancer in Study

Significant weight loss may not protect an obese person from cancers of the colon or liver, according to a recent study in obese mice. The study, “Weight loss following diet-induced obesity ... Read more

November 10, 2016

Emulsifiers Promote Colon Cancer in Mice by Triggering Inflammatory Gut Bacteria

Food additives called emulsifiers may be behind the increase in colon cancer seen in recent decades, as researchers discovered that they trigger low-grade gut inflammation and promote tumor formation in mice. ... Read more

November 8, 2016

Fat in Feces May Be Key to New Noninvasive Colorectal Cancer Diagnostic Method

A team of researchers recently discovered a novel noninvasive method that could provide early-stage diagnosis of colorectal cancer. They identified a class of molecules in mouse model feces that point ... Read more

November 3, 2016

Massachusetts Health Insurance Reform, Model for ACA, Seen to Improve Colon Cancer Care

A 2006 Massachusetts health care reform, which served as model for the Affordable Care Act (ACA), was associated with higher surgery rates and a lower probability of emergency surgeries for colorectal cancer, according ... Read more

November 1, 2016November 2, 2016

Selenium Does Not Prevent Colon Cancer, But Does Increase Risk of Type 2 Diabetes

Selenium, used as a nutritional supplement for decades with the belief it significantly lowered the risk of colorectal cancer, does not. Worse, in people with an adequate selenium intake, it ... Read more

October 27, 2016

Colon Cancer Patients Who Lack Emotional Support Have Much Greater Risk of Depression, Study Finds

Findings from the Colorectal Wellbeing Study indicate that after surgery, many colon cancer survivors experience a lack of affection and emotional and practical support, often resulting in depression and anxiety. These ... Read more

October 25, 2016

Colon Cancer Metastasis Co-opts Existing Blood Vessels to Grow, Resists Specific Therapies

Researchers may have unraveled the mechanism by which tumors resist anti-angiogenic agents (drugs that prevent tumor growth by impairing the formation of new blood vessels). According to the study “Vessel co-option mediates ... Read more

October 20, 2016

Camptosar, FOLFOX Chemo Combo Improves Advanced Colon Cancer Outcomes

First-line treatment of advanced colorectal cancer with FOLFOXIRI chemotherapy plus Avastin (bevacizumab) in a Phase 2 clinical trial showed improvements in patient response rate and progression-free survival, according to recently ... Read more

October 18, 2016October 18, 2016

Cancer Cell ‘Ferment’ Sugar to Speed Their Metabolism and Spread, Study Reports

Cancer cells are known to be able to speed up their metabolism, reprogramming it so they can proliferate more quickly. Now, researchers have identified one way that tumors alter their metabolism — fermenting rather than burning ... Read more

October 13, 2016

Researchers Find Key Protein that May Halt Colon Cancer Progression

Researchers have identified a protein that can inactivate one of the main pathways involved in the development and progression of colorectal cancer, a finding that may lead to the development ... Read more

October 11, 2016

Nintedanib Fails to Improve Overall Survival of Colon Cancer Patients, Trial Finds

Patients with metastatic colorectal cancer who no longer respond or tolerate other available treatments do not benefit more from nintedanib plus best supportive care (BSC) than from BSC alone, according to recent results ... Read more

October 6, 2016

To Prevent Colon Cancer, Physician Advises, ‘Listen to Your Gut’

Physicians at the University of Texas Southwestern Medical Center in Dallas, are calling for people to “listen to their gut” because those who pay attention to their digestive system’s normal behavior are ... Read more

October 4, 2016October 4, 2016

Combo Therapy Using Nanoparticles Shows Potential to Treat Advanced Colon Cancers

Though immune checkpoint inhibitors are deemed as especially promising in a number of cancers, the therapy often fails to exert an effect in more lethal cancers. Recently, researchers found that ... Read more

September 29, 2016September 29, 2016

Nanoparticles Derived from Ginger Safely Help Chemo Kill Colon Cancer Cells in Early Study

Nanoparticles derived from edible ginger effectively delivered the chemotherapy agent Adriamycin (doxorubicin) into tumor cells in a mouse model of colon cancer, inducing tumor cell death while largely sparring healthy cells, a new ... Read more

September 27, 2016

Surgical Removal of Primary Tumor in Colon Cancer Patients Doesn’t Improve Survival, Study Finds

Primary tumor resection (surgical removal of the original tumor) does not improve survival compared with chemotherapy in patients with metastatic colon cancer, according to the results of an observational cohort ... Read more

September 22, 2016September 22, 2016

Exercise May Help Prevent Alcohol-related Colon Cancer Deaths

Even moderate levels of exercise prevent some of the detrimental effects of drinking alcohol, such as the increased risk of dying from cancer. The findings are particularly relevant to colon ... Read more

September 20, 2016

Study Looks Beyond Aspirin’s Ability to Fight Colon Cancer

Aspirin’s ability to prevent cardiovascular disease and colon cancer is a known attribute of the pain reliever, but researchers do not fully understand how it exerts such diverse benefits. Now, a study ... Read more

September 15, 2016September 15, 2016

Researchers Learn How Colorectal Cancer Cells Resist Chemotherapy

Researchers have uncovered an additional way through which colorectal cancer cells may acquire resistance to treatment. According to a recent study, published in Oncotarget, the cells that compose the tumor ... Read more

September 13, 2016September 13, 2016

Mutations Unique to African-Americans with Colon Cancer Can Also Make It Aggressive

Last year, researchers at University Hospital Seidman Cancer Center and Case Western University identified gene mutations that are unique to colon cancers in African-American patients, making it almost a different ... Read more

September 6, 2016September 6, 2016

Colorectal Cancer Results When Retinoic Acid Is Lost, an Effect Caused by Inflammation

Retinoic acid, a metabolite derived from vitamin A, protects both mice and humans from developing colorectal cancer, according to the results of a new study that also showed that cancer patients ... Read more

August 2, 2016August 2, 2016

Glycosylation-associated Gene Mutations Discovered as New Targets in Colon Cancer

Though the molecular principles of dysfunctional protein glycosylation and the way its enzymatic mechanism is known to cause tumors in such cancers as colorectal cancer (CRC) is not completely understood, the recent study “Biochemical and functional ... Read more

May 19, 2016May 19, 2016

Burden of Colorectal Cancer Greatest in the Medicare Low-income American population

In the United States. colorectal cancer (CRC) is the second leading cause of death related to cancer. Estimates indicate that 49,190 American individuals will die from CRC in 2016. The burden ... Read more

May 4, 2016May 4, 2016

Colon Cancer Linked in Study to Mutations Caused by Imbalance in DNA Building Blocks

Proper balance among the four DNA building blocks, known as dNTPs, needs to be maintained during cell replication to avoid potential mutations. Now, researchers at Umeå University in Sweden have found that a disruption ... Read more

April 19, 2016April 19, 2016

Gene Variant May Contribute to Increased Colorectal Cancer Risk in African-Americans

Wistar Institute researchers have identified a single variant in an important tumor suppressor gene only found in Africans and African-Americans that might explain disparities in the incidence of certain cancers ... Read more

April 5, 2016April 5, 2016

Mutated Glycosyltransferases Might Contribute to Colon Cancer

Faulty protein glycosylation – a process of protein modification– is a hallmark of several cancer forms. But knowledge of how the complex molecular processes might contribute to cancer is sparse. In ... Read more

March 28, 2016March 28, 2016

For Colon Cancer with Liver Metastisis, Immunotherapy Combined with RFA May Benefit Patients

Researchers at the University of Pittsburgh found that radiofrequency ablation (RFA) combined with an immune checkpoint inhibitor resulted in a stronger antitumor immunity with extended survival in human samples of ... Read more

March 2, 2016March 2, 2016

Colon Cancer Gene Found in 18th Century Hungarian Mummified Tissues

Genetic predisposition to colorectal cancer was recently discovered in an 18th century Hungarian mummy. The findings were published in PLOS ONE journal, titled “Detection of a Tumor Suppressor Gene Variant ... Read more

February 23, 2016February 23, 2016

For National Colon Cancer Awareness Month in March, Here’s How to Get Involved

March was officially established as National Colon Cancer Awareness Month in 2000, and 16 years later, the event has grown to be a rallying point for the colon cancer community. Thousands of members, including ... Read more

February 9, 2016February 9, 2016

Promising Colorectal Cancer Therapy That Targets Cancer Stem Cells Moves Forward With Company’s 3rd Patent

Propanc Health Group Corporation, a Melbourne, Australia-based healthcare company focusing on the development of treatments for pancreatic, ovarian, and colorectal cancer treatments, announced it has filed a third patent on the use of PRP, ... Read more

January 25, 2016January 25, 2016

Molecular Link Between Obesity and Increased Risk of Colon Cancer Uncovered

Thomas Jefferson University researchers have found the molecular connection between obesity and an increased risk of colorectal cancer, while also identifying an FDA-approved drug that could prevent the cancer from developing. ... Read more

January 12, 2016January 29, 2016

Colon Cancer and Immune System’s Response to Tumor Development

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are reporting a key finding about the immune system and how it responds to tumor development, ... Read more

January 3, 2016January 4, 2016

Colorectal Cancer Resistance to Treatment May Have Molecular Cause

University of Texas MD Anderson Cancer Center researchers have linked epidermal growth factor receptor regulation to colorectal cancer tumorigenesis, poor patient outcomes, and resistance to treatment with cetuximab (Erbitux). The ... Read more

November 11, 2015November 25, 2015

Noninvasive Colorectal Cancer Screening of Benefit to Remote Native Alaskans

Findings from a recent study published in the journal Mayo Clinic Proceedings revealed that the cologuard stool DNA testing for colorectal cancer (CRC) is a highly accurate non-invasive screening option for ... Read more

October 19, 2015November 25, 2015

WARF Awards Colon Cancer Detection Research

The Wisconsin Alumni Research Foundation (WARF) granted an Innovation Award to researchers working on a blood test to detect colon cancer. The studies being conducted by biochemistry Professor Michael Sussman and his ... Read more

September 17, 2015September 17, 2015

Researchers Find Novel Protein With Implications In Colorectal Cancer

Researchers at the University of California, San Diego School of Medicine have come across a new protein pathway which could be a precursor for the initiation and progression of colorectal cancer while aiding to predict survival ... Read more

September 1, 2015September 1, 2015

Study Evaluates Age-Related Gut Modifications

The human gut microflora is responsible for maintaining many vital functions necessary for homeostasis. Digesting food, protection from foreign pathogens, providing immunity are some of the major functional attributes of gut microbes. Though ... Read more

August 18, 2015August 27, 2015

Roswell Park Scientists Develop Mobile Application Software for Colon Cancer Survivors

Scientists at the Roswell Park Cancer Institute (RPCI) in Buffalo, New York have developed a post-operative survival calculator that they have integrated into a mobile application compatible with smartphone technology. ... Read more

August 7, 2015August 31, 2015

Prevention of Thromboembolism After Surgery is Not Optimal, According to Study

Venous thromboembolism (VTE) is a serious complication associated with surgery performed in the large intestine (colorectal surgery) and its prevention has been promoted as a measure of utmost importance regarding patient safety by several ... Read more

July 22, 2015July 22, 2015

Novel Therapeutic Strategies for Colorectal Cancer Based On Newly Discovered Protective Gene

Researchers at St. Jude Children’s Research Hospital recently published in the journal Cell the discovery of a protective gene against colorectal cancer which may open alternative avenues towards novel therapeutic strategies. The ... Read more

July 1, 2015July 2, 2015

CTCA initiates New Clinical Study of Immunotherapy Combined With Chemotherapy

Cancer Treatment Centers of America (CTCA) recently announced it will begin a Phase Ib/II clinical trial using a novel immunotherapy for the treatment of patients with advanced kidney, pancreatic, colorectal carcinoma and ... Read more

June 29, 2015June 29, 2015

Restoring Single Gene Expression Sufficient to Block Colorectal Cancer Progression

In a new study entitled “Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer” a team of researchers showed that restoring the activity of a key gene, ... Read more

June 24, 2015June 26, 2015

Researchers Identify New Stem Cell Population Responsible For Colon Cancer

An international research team led by Timothy C. Wang from Columbia University identified a new cancer-initiating stem cell population in the colon and intestine. The study entitled “Krt19+/Lgr5– Cells Are ... Read more

June 22, 2015February 2, 2016

Frisbie Memorial Hospital Offers Virtual Colonoscopy For Colorectal Cancer Screening

Rochester, New Hampshire based Frisbie Memorial Hospital is now using low-dose CT scanning as a follow-up tool for colorectal cancer screening. The hospital says the procedure does not replace conventional ... Read more

June 22, 2015June 22, 2015

Genetic Test May Improve Patient’s Response to Metastatic Colorectal Cancer Treatment

A research team from the University of California San Diego identified biomarkers that may predict the response of metastatic colorectal cancer (mCRC) patients to chemotherapy. The results entitled “ERCC1 and TS ... Read more

June 17, 2015June 22, 2015

Cinnamon Component Prevents Colorectal Cancer In Mice

A research project conducted at the University of Arizona College of Pharmacy and the UA Cancer Center suggests that a substance present in cinnamon can act as a potent inhibitor of colorectal cancer. Drs. Georg ... Read more

June 12, 2015July 2, 2015

Genetic Biomarker May Predict Cancer Patients’ Response to Immunotherapy Drug

Researchers from Johns Hopkins Kimmel Cancer Center recently presented results from a Phase II clinical trial showing that in patients with colorectal cancers (CRCs) and other cancers for whom standard therapies ... Read more

June 9, 2015July 2, 2015

Genetic Risk Score Predicts Appropriate Age to Begin Colorectal Cancer Screening

Models to predict the risk of patients developing colorectal cancer are powerful tools that can be used to help augment screening and prevention strategies. A group of researchers from Fred ... Read more

June 1, 2015

Entolimod in Colorectal Cancer Treatment- Novel Results Presented At ASCO

During the 51st Annual Meeting of the American Society of Clinical Oncology (ASCO) a research team led by Alex A. Adjei, MD, PhD, FACP, of Roswell Park Cancer Institute (RPCI) ... Read more

May 31, 2015

Colon Cancer Diagnosis With Lumninescent Bacteria: Modified Probiotics Can Successfully Detect Tumors In Liver

Engineers from the University of California at San Diego (UCSD) and MIT devised a new strategy to detect cancer that has metastasized to the liver using probiotics, beneficial bacteria such as those found in yogurt. The ... Read more

May 27, 2015

Walnuts Slow Colorectal Cancer Growth In Mice

In a recent study published in the Journal of Nutritional Biochemistry a research team  led by Dr. Christos Mantzoros from Beth Israel Deaconess Medical Center, Harvard Medical School found that a diet ... Read more

May 22, 2015May 22, 2015

Roche Receives FDA Approval For Its Cobas KRAS Mutation Test

Roche recently announced that the United States Food and Drug Administration (FDA) has approved its cobas KRAS Mutation Test to be used for diagnostic purposes. This real-time PCR test was developed to find KRAS mutations in tumor ... Read more

May 20, 2015May 20, 2015

Novel Non-invasive Screening of Colon Cancer Highlighted As Alternative to Colonoscopy for African Americans

A research team from the University Hospitals (UH) Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine recently discovered that a novel non-invasive method for screening colon ... Read more

May 18, 2015May 22, 2015

Drug Combination Can Extend Survival in Metastatic Colorectal Cancer Patients

Results from a recent international clinical trial led by investigators at the Dana-Farber Cancer Institute showed that a medication developed 50 years ago and abandoned due to its toxicity, might extend ... Read more

May 15, 2015May 15, 2015

Promising Antibody Therapy for Resistant Advanced Colorectal Cancer

A recent study entitled “Safety and Activity of the First-in-Class Sym004 Anti-EGFR Antibody Mixture in Patients with Refractory Colorectal Cancer” showed that a specific therapy based on Sym004 antibody mixture ... Read more

May 13, 2015May 13, 2015

Researchers Discover a New Therapeutic Role for a Chemotherapy Drug in Colon Cancer

A team led by researchers at the Karolinska Institute in Sweden and Nanyang Technological University in Singapore recently reported that an already existing chemotherapy drug for the treatment of leukemia ... Read more

May 11, 2015May 11, 2015

Anti-Cancer Stem Cell OH14 Licensed to Tiziana from Cardiff University

A new compound developed in a laboratory at Cardiff University holds great potential for fighting colon cancer. The compound, OH14, in now under license at Tiziana Life Sciences, which is ... Read more

May 8, 2015May 8, 2015

US San Diego School of Medicine Researchers Find That Patients With GISTs are More Likely to Develop Other Cancers

In a recent study published in the journal Cancer, a research team from UC San Diego School of Medicine conducted the first population-based study characterizing the association and temporal relationship between ... Read more

May 6, 2015May 6, 2015

Novel Anticancer Small Molecule Could Overcome Treatment Resistance in Colorectal Cancer

In a recent study published in the journal Molecular Cancer, a research team led by Fengzhi Li, PhD, of Roswell Park Cancer Institute (RPCI) found that a novel anticancer small ... Read more

May 4, 2015May 4, 2015

PlasmaTech’s ProctiGard Can Prevent Radiation Therapy Side-Effects in Colon Cancer Patients

The National Cancer Institute at the National Institutes of Health estimates that there are more than 250,000 new cases of colon, rectal, bladder, cervical, prostate, testicular and endometrial cancer diagnosed ... Read more

May 1, 2015May 1, 2015

FDA Approves New Monoclonal Antibody For Colon Cancer Treatment

The U. S. Food and Drug Administration (FDA) has recently approved a new drug for colon cancer. According to an announcement on the FDA website, the approval has been granted for ... Read more

April 30, 2015April 30, 2015

Two-Week International Diet Swap Reveals Potential Effects Of Food On Colon Cancer Risk

According to an international study published in Nature Communications conducted by scientists at the University of Pittsburgh School of Medicine, African-Americans and Africans who swapped their regular diets for just 2 weeks altered their risks of developing colon ... Read more

April 29, 2015April 29, 2015

Researchers Identify Toxic Mushroom-Based Drug To Fight Colorectal Cancer

A toxin called alpha-amanatin, derived from “death cap” mushrooms was considered for some time as a potential treatment for colorectal cancer. But since the toxin is known to cause liver toxicity, ... Read more

April 28, 2015April 28, 2015

FDA Highlights Higher Incidence of Colorectal Cancer in Minorities

The U.S. Food and Drug Administration (FDA) recently published an article highlighting the incidence of colorectal cancer, particularly among minorities. The study entitled “Colorectal Cancer: What You Should Know” was published ... Read more

April 27, 2015April 27, 2015

Silibinin from Milk Thistle Extract Halts Colon Cancer Stem Cells

A nontoxic chemical extracted from milk thistle, a purple flower that grows around the world, may help stop the growth of colon cancer stem cells. Silibinin, the purified chemical, was shown ... Read more

April 24, 2015April 27, 2015

Colorectal Cancer Metabolism Regulated by Specific Long Non-Coding RNA Molecule

The University of Texas MD Anderson Cancer Center recently announced that a collaborative study involving MD Anderson researchers discovered that a specific RNA molecule is capable of regulating cancer metabolism ... Read more

April 23, 2015April 27, 2015

Novel Biomarkers for Colorectal Cancer Detection Discovered

Due to the low response rates of colorectal cancer patients for different drug regimens, a team of researchers at Champions Oncology and InSilico Medicine examined if biomarkers and biological signals in ... Read more

April 22, 2015April 22, 2015

A New Cold Plasma Apparatus To Kill Cancer Cells In Colon Cancer

A new cold plasma device, Canady Helios Cold Plasma Scalp, developed by the US Medical Innovations (USMI) family of companies, was used in a patient diagnosed with inoperable colon cancer. The ... Read more

April 21, 2015April 21, 2015

DiaCarta and University of Potsdam Collaborate on Novel Early Colon Cancer Detection Test

California-based molecular diagnostics company DiaCarta Inc. and the University of Potsdam in Germany have recently announced an exclusive license agreement for the development and commercialization of a non-invasive diagnostic test for early detection ... Read more

April 20, 2015April 20, 2015

Exercise is Beneficial for Colorectal Cancer Survivors, According to Study

According to two recent studies conducted by an American and Dutch team and published in the Journal of Cancer Survivorship, exercise is beneficial for colon and prostate cancer survivors. In the ... Read more

April 17, 2015April 18, 2015

“Nontoxic” Salmonella Kills Colon Cancer Cells

Colon cancer cells are no match for Salmonella enterica. However, there is risk for using Salmonella as part of cancer therapy, as the microbe wreaks havoc on the human body. It ... Read more

April 16, 2015April 16, 2015

New Protein Implicated in Colon Cancer Metabolism Upon Excess of Nutrients

A new study published last week in the Developmental Cell journal offers new possibilities of therapy development for diseases such as colon cancer and diabetes mellitus. Senior author Nabil Djouder and his team from ... Read more

April 15, 2015April 15, 2015

Researchers Target Protein To Stop Spread Of Colon Cancer

Researchers have developed the podocalyxin antibody, demonstrating that it slows both tumor growth and spread by comparing cancer metastases with control samples. These findings were recently published in the Breast Cancer Research journal and may lead to major developments ... Read more

April 14, 2015April 14, 2015

mTOR Inhibitors Revealed To Be Strong Anti-Colon Cancer Agents

Colon cancer is often associated with the mammalian target of rapamycin (mTOR), a serine/threonine kinase activated in a range of cellular activities such as growth, proliferation, and migration. A new ... Read more

April 13, 2015April 13, 2015

Pancreatic Cancer Drug Works Against Accumulation of Malignant Ascites Fluid in Colon Cancer Patients

Research supported by PharmaCyte Biotech, Inc., a biotechnology company developing treatments for cancer patients, determined that the company’s pancreatic cancer treatment is able to reduce malignant ascites’ fluid accumulation. Ascites consist of a fluid build-up in ... Read more

April 10, 2015April 10, 2015

Imatinib Inhibits EphB Abl Signaling Pathway and Suppresses Colorectal Cancer

Researchers from Karolinska Institutet in Sweden and Nanyang Technological University in Singapore showed that the drug Imatinib, a tyrosine kinase inhibitor used in leukemia, can inhibit the development of intestinal ... Read more

April 9, 2015April 9, 2015

Overweight Girls More Likely to Develop Colorectal Cancer

Overweight children and youngsters may have a higher risk of developing colorectal cancer later in life, according to a study recently published in Cancer Epidemiology Biomarkers and Prevention. The conclusions mainly involved women, ... Read more

April 7, 2015April 7, 2015

Fasting Combined With Less-Toxic Drugs Effective Alternative to Chemotherapy

A multinational collaboration between the University of Southern California, Lizzia Raffaghello at the G. Gaslini Institute in Italy and the laboratories of Alessio Nencioni at University of Genova, showed that a less-toxic class of ... Read more

April 6, 2015April 8, 2015

Study Points Out New Role For Gene In Colon Cancer Suppression

A novel function in a previously known gene may help cells divide normally, but its absence might cause tumors, particularly in colon cancer. These are the results from a team of The ... Read more

April 6, 2015April 6, 2015

Clinical Practice Guidelines on Molecular Marker Tests for Colorectal Cancer Open to Public Comment

An expert panel recently released a clinical practice guideline draft for the assessment of molecular markers in patients with primary or metastatic colorectal cancer. The document is entitled “Guideline on the ... Read more

April 2, 2015April 2, 2015

Fitness Level Associated With Lower Risk Of Colorectal Cancer In Men

A recent study showed that middle aged men with high fitness levels have lower risks of developing colorectal cancer. Further, higher fitness levels are associated with lower death rates in men diagnosed with cancer ... Read more

April 1, 2015April 1, 2015

Fecal Immunochemical Test Improves Bowel Cancer Screening Rates

Findings from a large pilot study on a novel bowel cancer-screening test showed it could increase the number of participants across population groups. These results will be presented by researchers from Queen Mary ... Read more

March 31, 2015March 31, 2015

E. coli Linked to Endoscopes in Colon Cancer Screenings

Individuals looking to decrease their risk for colon cancer by opting for a preventative colonoscopy may be at a risk for exposure to Escherichia coli. A hospital in Washington state ... Read more

March 30, 2015March 30, 2015

Genetic Mutations Associated With Liver Metastasis From Primary Colorectal Cancer Discovered

In a recent study, researchers were able to characterize genetic alterations associated with liver metastasis from primary colorectal cancer . The new finding, published in the online version of the journal ... Read more

March 27, 2015March 27, 2015

Ferndale Healthcare’s Education Campaign Brochure Helps Alert Consumers to Signs & Symptoms of Colon Cancer

In 2000, President Clinton announced that March would be officially designated National Colon Cancer (CC) Awareness Month.  Since the announcement, March has become a time where public health advocates, healthcare providers, survivors, ... Read more

March 26, 2015March 26, 2015

Metformin And Vitamin D3 Combined Show Promise In Preventing Colorectal Cancer

A recent study showed that the anti-diabetic drug metformin and vitamin D3 are promising for colorectal cancer prevention. The study was published in the Cancer Prevention Research journal. According to Dr. Li Li, a researcher at the Case ... Read more

March 25, 2015March 25, 2015

‘Getting To Zero’ Meeting Addresses Recommendations To Stop Duodenoscope Infections

The “Getting to Zero” meeting was recently convened by the American Gastroenterological Association (AGA) Center for GI Innovation and Technology where best practices to prevent antibiotic-resistant infections after duodenoscopies were discussed. The meeting ... Read more

March 24, 2015March 24, 2015

Researchers Develop Strategies to Improve Colorectal Cancer Screening in Low-Income and Minority Populations

Screening for colorectal cancer has saved millions of lives, however, not everyone has access or is aware that other screening procedures exist. Allen Greiner, M.D., M.P.H., who is a member of ... Read more

March 23, 2015March 23, 2015

Genetic Variants Determine Aspirin and NSAIDs Benefits in Colon Cancer Risk

In a recent study entitled “Association of Aspirin and NSAID Use With Risk of Colorectal Cancer According to Genetic Variants,” published in the Journal of the American Medical Association by Indiana University ... Read more

March 20, 2015March 20, 2015

Possible Association Between Genetic Alterations and Colorectal Cancer Prognosis

A team of researchers from the Princess Margaret Cancer Centre, the University of Toronto and Memorial University in Canada conducted a study on the possible association between specific genetic alterations and ... Read more

March 19, 2015March 19, 2015

MSI2 RNA-binding Protein the New “kid on the block” in Colon Cancer

A new study on Colon Cancer revealed a novel player in the development of the disease, a RNA-binding protein Musashi homolog 2 (MSI2). The study entitled “Transformation of the intestinal ... Read more

March 18, 2015March 18, 2015

Study Highlights Long-term Survival Rates for Invasive Cancers Such as Colon Cancer

The Morbidity and Mortality Weekly Report recently included a study from Centers for Disease Control and Prevention (CDC) entitled “Invasive Cancer Incidence and Survival — United States, 2011” published by ... Read more

March 17, 2015March 17, 2015

Mutations in TP53 Gene Associated with Early-Onset Colorectal Cancer

A new study recently published in the journal JAMA Oncology revealed the frequency of mutations in the germline TP53 gene in patients diagnosed with early-onset colorectal cancer. The study is ... Read more

March 16, 2015March 16, 2015

Reaching ’80 Percent By 2018′ Could Prevent More Than 20,000 Yearly Colorectal Cancer Deaths

A recent study led by researcher Ahmedin Jemal and the American Cancer Society concluded that if an 80 percent rate of colorectal cancer screening is reached by the year of 2018, more than ... Read more

March 13, 2015March 13, 2015

Physicians Join to End Colorectal Cancer Myths

During Colorectal Cancer Awareness Month being celebrated this March, specialists for the disease are joining efforts to improve awareness about preventing the disease within the general public. Experts from Northwestern Memorial Hospital recently hosted a free ... Read more

March 12, 2015March 12, 2015

Natural Language Processing Software Could Improve Colon Cancer Detection

Researchers at the Regenstrief Institute have developed and tested a precise system that can track colonoscopy quality and appropriate procedure intervals, improving health outcomes and lowering overall costs. The system ... Read more

March 11, 2015March 11, 2015

Single-Site Laparoscopic Surgery to Treat Colon Cancer

In 2000, President Clinton announced that March would be officially designated as National Colon Cancer (CC) Awareness Month.  Since this announcement was made, March has become a time where public ... Read more

March 10, 2015March 10, 2015

Texas A&M Expands Colon Cancer Screening Program

The Texas A&M Health Science Center announced it is expanding its Cancer Screening, Training, Education and Prevention (C-STEP) program to an additional 10 counties in Texas, reaching a total of 17. The ... Read more

March 9, 2015March 9, 2015

Increased Adjuvant Therapy For Localized Gastrointestinal Tumors (GISTs) Associated With Improved Survival Outcomes

According to a recent population-based study published in the American Journal of Clinical Oncology, adjuvant therapy in localized gastrointestinal tumors (GISTs) has increased over time, with patients showing an improved survival ... Read more

March 6, 2015March 6, 2015

Rutgers Cancer Institute Announces Clinical Trial Testing Novel Drug Against Solid Tumors

Rutgers Cancer Institute located in New Brunswick, New Jersey, announced it is opening up enrollment for a new clinical trial to investigate ONC201, a novel anti-cancer drug designed by Oncoceutics ... Read more

March 5, 2015March 5, 2015

Amgen’s Vectibix Approved For Metastatic Colorectal Cancer Treatment

Amgen, a pharmaceutical company devoted to the development of novel human therapeutics for serious diseases, recently announced that the Committee for Medicinal Products for Human Use (CHMP) at the European ... Read more

March 3, 2015March 3, 2015

NYU Langone Gastroenterologist Offers Recommendations for Colon Cancer Prevention

March has been declared national colon cancer awareness month, and as part of the effort to raise awareness of the disease, director of the Division of Gastroenterology at NYU Langone Medical ... Read more

March 2, 2015March 2, 2015

Neighbor Tissue in Colon Tumors Dictates Relapse Prognosis

Researchers at the Institute for Research in Biomedicine (IRB) Barcelona, Spain have recently published new research in the journal Nature Genetics where they highlight the possibility of classifying colon tumors into good or bad prognosis based ... Read more

February 27, 2015February 27, 2015

Study Underscores Factors Influencing Family Involvement In Colon Cancer Patients’ Decisions

A recent study published in Cancer provides important insights into how family members and cancer patients make decisions together relative to treatment options. This information might help physicians understand patients’ preferences regarding their care, especially since family ... Read more

February 26, 2015February 26, 2015

Fungal Infection Mimics Colorectal Cancer, According to Case Report

Researchers at the University of Arizona reported a case study of a male patient with a fungal infection that resembled colorectal cancer. The study was published in the journal BMC Research ... Read more

February 25, 2015February 25, 2015

Researchers Examine Oncological Resection Principles In Emergency Surgical Treatment of Advanced Colorectal Cancer Patients

Researchers from the University of Sao Paulo in Brazil examined the oncological resection principles affecting outcomes in emergency surgical treatment of patients with advanced colorectal cancer. The study titled “Can ... Read more

February 24, 2015February 24, 2015

Oncolytics Completes Patient Enrolment in Phase II Trial Of Reolysin For Colorectal Cancer Treatment

Oncolytics Biotech Inc. recently announced it completed patient enrollment in its randomized Phase 2 study of Reolysin to treat patients suffering with metastatic or advanced colorectal cancer. This trial is being sponsored and conducted by ... Read more

February 23, 2015February 23, 2015

Protein Found to Promote Colon Cancer Migration and Recurrence

Researchers from the Chinese Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital in Chengdu and Nanfang Hospital, Southern Medical University, discovered that the protein LIN28B is able to induce ... Read more

February 20, 2015February 20, 2015

Intracellular Calcium Affects Colon Cancer Cell Motility

A calcium supplement a day may not make metastatic colon cancer go away. In fact, as reported in a new article from Gachon University in the Republic of Korea, dietary ... Read more

February 19, 2015February 19, 2015

Combination of BRAF Inhibitors Might Improve Colorectal Cancer Treatment

A research team at Albert-Ludwigs-University in Germany led by Dr. Tilman Brummer studied the role of BRAF mutations in metastasis of colorectal carcinoma using a three-dimensional (3D) tissue culture model. The ... Read more

February 18, 2015February 18, 2015

Fearing Cancer Can Both Encourage or Discourage Screening

Concern about the possibility of developing cancer often times leads to colon cancer screening. However, the same concern also makes people less likely to actually undergo the exam. Those are the conclusions of research conducted at ... Read more

February 17, 2015February 17, 2015

Multidisciplinary Care for Patients Undergoing Colorectal Surgery Reduces Length of Stay, Medical Costs

According to a recent study published in the Journal of the American College of Surgeons, a new healthcare approach based on multidisciplinary care management for patients in need of colorectal surgery results ... Read more

February 16, 2015February 16, 2015

Chronic Inflammation May Drive Colon Cancer

In a recent study entitled “Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17–producing CD4+ T cells,” a research team identified that a specific type of immune ... Read more

February 13, 2015February 13, 2015

Study Discovers Origins of Colorectal Cancer Cells

A group of cancer researchers from Keck Medicine of the University of Southern California (USC) have managed to trace the origins of colorectal cancer cells, finding important clues that could explain why tumor ... Read more

February 12, 2015February 12, 2015

Aggressive Cancer Predisposition in Children Associated With Fatal Mutations

A recent study published in the journal Nature Genetics, focused on children with an aggressive cancer predisposition and the associated underlying mutations. The study is entitled “Combined hereditary and somatic mutations ... Read more

February 11, 2015February 11, 2015

‘Western’ Diet Linked To Higher Risk Of Colon Cancer Recurrence

A group of researchers from the Dana-Farber Cancer Institute published a report stating that the “Western Diet,” high in red meat, refined grains, fatty products and desserts, might increase the odds of early death and disease ... Read more

February 10, 2015February 10, 2015

Researchers Reveal the Mechanism Behind Targeted Cancer Therapy Drug Resistance

Researchers at the University of California, San Francisco (UCSF) recently published in the journal Nature Genetics their findings on a protein known as YAP and its role in the development of ... Read more

February 9, 2015February 9, 2015

Study Helps Understand Stem Cell Regulation in Intestinal Cancer

A research team led by Dr. Jorge Moscat, PhD., program director of the Cell Death and Survival Networks Program at Sanford-Burnham Medical Research Institute (Sanford-Burnham), has made an important discovery ... Read more

February 6, 2015February 6, 2015

Colorectal Cancer Patients Who Smoke Have Higher Risk of Death

A new study entitled “Active Smoking and Mortality Among Colorectal Cancer Survivors: The Cancer Prevention Study II Nutrition Cohort” reports that colorectal cancer survivors who smoke cigarettes have double risk ... Read more

February 4, 2015February 4, 2015

Cytotoxic T Cells Indicate Favorable Prognosis in Colorectal Cancer

A research team from Heidelberg and Dresden has found a connection between increased levels of TNF alpha in tumor tissue and an increased number of activated cytotoxic T cells that ... Read more

February 3, 2015

FOXFIRE And FOXFIRE Global Finish Colorectal Cancer Patient Enrolment

Sirtex Medical Limited recently announced they completed patient enrolment in two large clinical studies: FOXFIRE and FOXFIRE Global. These two trials are evaluating a combined approach of liver radiation using SIR-Spheres ... Read more

February 2, 2015February 2, 2015

MicroRNA Biomarkers To Identify Colon Cancer Metastases

A recent study published in the Journal of the National Cancer Institute by Baylor Research Institute investigators has identified novel metastasis-specific microRNA signatures in samples of primary colorectal cancers that ... Read more

January 30, 2015January 30, 2015

High-Quality Cancer Care Erases Racial Disparities in Colon Cancer Survival,

A recent study published in the Journal of Clinical Oncology has demonstrated that the gap between African-American colon cancer patients’ survival and white patients can be reduced upon the delivery ... Read more

January 29, 2015January 29, 2015

Colorectal Cancer Metastasis Associated With Liver Metabolic Processes

Recent findings published in Cell by Rockefeller researchers have shown that metabolic processes occurring during liver metastasis of colorectal cancer can be crucial to activate starving transient cancer cells, allowing ... Read more

January 28, 2015January 28, 2015

New Strategy for Ras-Associated Colon Cancer Treatment

Colon cancer is one of the three highly fatal cancers caused by a protein called Ras. Professor Dimitrios Stamou, head of a multidisciplinary team in bio-nanotechnology and nanomedicine at University ... Read more

January 27, 2015January 27, 2015

Hypertension and Proteinuria in Bevacizumab-Treated Metastatic Colorectal Cancer Patients

In a recent study titled “Correlation of Hypertension and Proteinuria with Outcome in Elderly Bevacizumab-Treated Patients with Metastatic Colorectal Cancer”, published in PlosOne, a team of Spanish researchers designed a ... Read more

January 26, 2015January 26, 2015

Study Reveals Protein Kinase C Role in Colon Cancer

Researchers at the University of California, San Diego School of Medicine made a surprising discovery that is published ahead of print in the prestigious journal Cell. The team found that a set ... Read more

January 23, 2015January 23, 2015

Trovagene Collaboates With Genomac To Test Colorectal Cancer Platform

Trovagene, Inc. has announced it will collaborate with the Genomac Research Institute, Prague, to test Trovagene’s Precision Cancer Monitoring equipment in early identification of gene mutations rendering lung and colorectal ... Read more

January 22, 2015

Trovagene Presented Clinical Result From Its Precision Cancer Monitoring Platform in Colorectal Cancer Patients

Trovagene, Inc., has presented the results of a clinical study during the 2015 Gastrointestinal Cancer Symposium held in San Francisco, CA, showing the efficacy of the company’s Precision Cancer Monitoring platform in ... Read more

January 21, 2015January 21, 2015

Study Finds Link Between Colon Cancer And Sedentary Habits

According to a new study published in the Annals of Internal Medicine by Canadian researchers, there is a serious risk of illness or even premature death from too much sitting ... Read more

January 20, 2015January 20, 2015

Gene Involved In Colon Cancer Progression and Chemoresistance Identified

Researchers from Shanghai Jiao Tong University, China, have identified p21-Activated kinase 6 (PAK6) as a predictor of 5-fluorouracil (5-FU) treatment response in colon cancer. Even though surgery is usually preformed ... Read more

January 19, 2015January 19, 2015

Vitamin D Can Enhance The Immune System, Protecting Against Colorectal Cancer

According to new research by Dana-Farber Cancer Institute investigators, vitamin D can exert a protective effect against colorectal cancer by enhancing the immune system’s capacity to detect cancer cells. The ... Read more

January 16, 2015January 16, 2015

Lower Surgery Rates Among Metastatic Colorectal Cancer Patients, But Improved Survival

Due to the medical advances in chemotherapy and the diverse biological agents available for managing metastatic colorectal cancer, patients are undergoing less tumor removal surgery, according to a study from The University of Texas MD Anderson Cancer ... Read more

January 15, 2015January 15, 2015

High Vitamin D Levels Increase Survival of Metastatic Colorectal Cancer Patients

A recent study, presented during the 2015 American Society of Cancer Oncology (ASCO) Gastrointestinal Cancers Symposium, San Francisco, has shown that metastatic colorectal cancer (mCRC) patients who had high levels ... Read more

January 14, 2015January 14, 2015

New Colorectal Cancer Gene Mutations in African American Patients Indentified

A team of researchers has identified new genetic mutations specific for colon cancer in African Americans, one of the populations with a higher incidence of this malignancy. The study, published ... Read more

January 13, 2015January 13, 2015

Chemoradiation Treatment Improves Overall Survival Rates for Rectal Cancer Patients

A recent study published in the International Journal of Radiation Oncology • Biology • Physics (Red Journal) has demonstrated that patients suffering from locally advanced rectal cancer who are treated with preoperative ... Read more

January 12, 2015January 12, 2015

Theralase Develops Promising Colon Cancer Therapeutic Technology

Theralase Technologies Inc. is advancing its pioneering studies on anti-cancer therapeutics using its leading technology, the Photo Dynamic Compounds, PDCs, that is equipped with a super-pulsed laser technology. The first clinical studies ... Read more

January 9, 2015January 9, 2015

Seven New KRAS Mutations Found In Colorectal Cancer

In a recent study titled “Novel KRAS Gene Mutations in Sporadic Colorectal Cancer” published in the PlosOne journal, an international team of researchers has reported seven new KRAS gene mutations ... Read more

January 8, 2015January 8, 2015

Healthy Dietary Habits May Lower Risk of Obesity-Related Cancers

A new study led by New York University researchers shows that a diet with low alcohol intake and with a high plant intake can help to reduce the risk of ... Read more

January 7, 2015January 7, 2015

Colon Cancer Affected By Number Of Stem Cell Divisions

A statistical-based computer model created by two scientists at the Johns Hopkins Kimmel Cancer Center places colon cancer in the category of cancers due to bad luck, environmental factors, and ... Read more

January 6, 2015

Researchers Review TRK Cancer Mutations As Targets In New Clinical Trials

A recent study published in the journal Cancer Discovery reviewed several clinical trials that are using drugs targeting the TRK gene for the treatment of different types of cancer, including ... Read more

January 5, 2015January 5, 2015

Taiho Oncology Submits New Drug Application To The FDA for Treatment of Refractory Metastatic Colorectal Cancer

Taiho Oncology, Inc. has finalized its New Drug Application (NDA) submission to the U.S. Food and Drug Administration (FDA) for its proprietary TAS-102 (trifluridine and tipiracil hydrochloride) for the treatment ... Read more

January 2, 2015January 2, 2015

Adiponectin Polymorphisms Are Linked To Colorectal Cancer Risk

In a recent study titled “Association Between Adiponectin Polymorphisms and the Risk of Colorectal Cancer”, published in Genetic Testing and Molecular Biomarkers, a team of researchers from Harbin Medical University, ... Read more

December 30, 2014December 30, 2014

Researchers Develop And Test A Novel Screening Kit for Colorectal Cancer

In a new study titled “The Usefulness of a Novel Screening Kit for Colorectal Cancer Using the Immunochromatographic Fecal Tumor M2 Pyruvate Kinase Test “, published in the Gut and ... Read more

December 29, 2014December 29, 2014

Researchers Find Genetic Determinants of Colorectal Cancer And Other Disorders

Researchers from the University of Toronto have developed a new computational technique that is able to pinpoint DNA mutations that can cause disease. The study, published in Science, reports on ... Read more

December 26, 2014December 26, 2014

High-Definition Scopes Efficiently Assess Intestinal Polyps

A new study entitled “Accuracy of in vivo colorectal polyp discrimination by using dual-focus high-definition narrow-band imaging colonoscopy” shows that current imaging techniques used in colonoscopies are capable of assessing the benign ... Read more

December 23, 2014December 26, 2014

Can Inflammation Causing Intestinal Bacteria Be Inherited?

A team of researchers from the University of Minnesota, along with international collaborators, has found that intestinal bacteria responsible for Crohn’s disease and ulcerative colitis (known as inflammatory bowel disease ... Read more

December 22, 2014December 22, 2014

Study Finds Link Between Selenium And Colorectal Cancer

A recent study published in the International Journal of Cancer by Newcastle University researchers found that high levels of selenium are correlated with a lower risk of colorectal cancer. The ... Read more