June 8, 2017August 24, 2022
Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

The MEK inhibitor Mekinist (trametinib) is to be tested in combination with Opdivo (nivolumab) — or Opdivo plus Yervoy (ipilimumab) — in colorectal cancer ... Read more
June 6, 2017
Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Certain patients who underwent surgery for lymph-node positive colon cancer (stage 3) may require only three months of chemotherapy after surgery ... Read more
June 1, 2017June 1, 2017
Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

The MEK inhibitor binimetinib will soon be tested in combination with Opdivo (nivolumab) plus Yervoy (ipilimumab) in colorectal cancer patients ... Read more
May 30, 2017
PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

Trovagene’s PCM-075 therapy for several blood cancers and solid tumors, including colon cancer, proved safe in a Phase 1 clinical ... Read more
May 25, 2017May 25, 2017
FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Colorectal cancer patients with unresectable or metastatic tumors bearing a genetic feature — microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) — ... Read more
May 23, 2017
Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Overweight boys have a higher risk of developing colon cancer in adulthood, but if they lose the extra pounds by ... Read more
May 18, 2017May 18, 2017
Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Tom Marsilje, who survived stage IV colorectal cancer (CRC), has joined forces with New York-based Fight Colorectal Cancer to help patients search for ... Read more
May 16, 2017
Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

The Colon Cancer Coalition, a nonprofit organization that encourages grassroots efforts to promote colon cancer awareness and screening, is partnering ... Read more
May 11, 2017
Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

A new European project aims to develop an innovative endoscope device that can detect and diagnose colorectal cancer in its early ... Read more
May 9, 2017
Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

People who eat healthy, exercise, and do not smoke are less likely to report a personal history of colorectal cancer ... Read more
May 4, 2017May 4, 2017
RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

Small molecule compounds known as RLR agonists, being developed by Kineta to treat colon cancer, were seen to kill cancer ... Read more
May 2, 2017May 2, 2017
New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research

MIT researchers using the CRISPR-Cas9 genome editing and organoid technology have developed a new mouse model with a cancer that ... Read more

December 6, 2016December 6, 2016

Diagnostic Agent Detects Colorectal Cancer Response to Therapy in 1 Day in Mice

A preclinical study showed that response of colorectal cancer to treatment can be detected after a single administration using the diagnostic agent TumorVue (99mTc-duramycin), developed by Molecular Targeting Technologies (MTTI). These ... Read more

December 1, 2016December 1, 2016

Synthetic Protein May Work as RAS Inhibitor to Treat Colon and Other Cancers

Nearly 30 percent of all cancers have activating mutations in the RAS family of proteins, but researchers have struggled to safely block these tumor-promoting proteins. But an approach taken by a team at University ... Read more

November 29, 2016November 29, 2016

Fine Line Seen Between Colon Cancer Suppression and Gut Renewal in Study

The gut has a remarkable capacity for regeneration after chemotherapy or radiation, thanks to a type of reserve stem cell. But while activating these cells could help patients heal after cancer treatment, ... Read more

November 22, 2016

European Clinicians Question Latest US Colorectal Cancer Screening Guidelines

Earlier this year, the U.S. Preventive Services Task Force (USPSTF) updated the recommendations for colorectal cancer screening. But European clinicians claim that USPSTF recommendations lack strength and quality of evidence. ... Read more

November 17, 2016

Left-sided Colon Cancer Associated with Better Prognosis than Right-sided, Study Finds

The side of origin of colon cancer has been associated with distinct genetic profiles and clinical presentations. Researchers have now shown that this impacts patients’ prognosis, with left-sided colon cancer associated ... Read more

November 15, 2016

Weight Loss After Obesity Fails to Protect Mice from Colon, and Possibly Liver, Cancer in Study

Significant weight loss may not protect an obese person from cancers of the colon or liver, according to a recent study in obese mice. The study, “Weight loss following diet-induced obesity ... Read more

November 10, 2016

Emulsifiers Promote Colon Cancer in Mice by Triggering Inflammatory Gut Bacteria

Food additives called emulsifiers may be behind the increase in colon cancer seen in recent decades, as researchers discovered that they trigger low-grade gut inflammation and promote tumor formation in mice. ... Read more

November 8, 2016

Fat in Feces May Be Key to New Noninvasive Colorectal Cancer Diagnostic Method

A team of researchers recently discovered a novel noninvasive method that could provide early-stage diagnosis of colorectal cancer. They identified a class of molecules in mouse model feces that point ... Read more

November 3, 2016

Massachusetts Health Insurance Reform, Model for ACA, Seen to Improve Colon Cancer Care

A 2006 Massachusetts health care reform, which served as model for the Affordable Care Act (ACA), was associated with higher surgery rates and a lower probability of emergency surgeries for colorectal cancer, according ... Read more

November 1, 2016November 2, 2016

Selenium Does Not Prevent Colon Cancer, But Does Increase Risk of Type 2 Diabetes

Selenium, used as a nutritional supplement for decades with the belief it significantly lowered the risk of colorectal cancer, does not. Worse, in people with an adequate selenium intake, it ... Read more

October 27, 2016

Colon Cancer Patients Who Lack Emotional Support Have Much Greater Risk of Depression, Study Finds

Findings from the Colorectal Wellbeing Study indicate that after surgery, many colon cancer survivors experience a lack of affection and emotional and practical support, often resulting in depression and anxiety. These ... Read more

October 25, 2016

Colon Cancer Metastasis Co-opts Existing Blood Vessels to Grow, Resists Specific Therapies

Researchers may have unraveled the mechanism by which tumors resist anti-angiogenic agents (drugs that prevent tumor growth by impairing the formation of new blood vessels). According to the study “Vessel co-option mediates ... Read more

Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research