December 19, 2014December 19, 2014

New Therapy Shows Promise In Colorectal Cancer Treatment

A team at Roswell Park Cancer Institute (RPCI) has published the results of a recent study in the Cancer Research journal, where they show that novel anticancer agent FL118 can ... Read more

December 18, 2014December 18, 2014

Bacterial Biofilms Linked To Colon Cancer, According To Researchers

A recent study titled “Microbiota organization is a distinct feature of proximal colorectal cancers”, published in the Proceedings of the National Academy of Sciences (PNAS), has found that bacterial biofilms ... Read more

December 17, 2014December 17, 2014

Study Finds TV Time Negatively Associated With Colorectal Cancer Survival

A recent study titled “Pre- and Postdiagnosis Physical Activity,Television Viewing, and Mortality Among Patients With Colorectal Cancer in the National Institutes of Health–AARP Diet and Health Study”, published in the Journal ... Read more

December 16, 2014December 16, 2014

Study Finds Hormone Loss Could Lead To Colon Cancer Progression

In a recent study published in the Cancer, Epidemiology, Biomarkers & Prevention journal, a team of researchers from Thomas Jefferson University showed that upon the loss of an essential hormone, ... Read more

December 15, 2014December 15, 2014

Study Finds Evidence For Testosterone Role in Colon Cancer Development

In a recent study titled “Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones”, published in the Proceedings of the National Academy of Sciences ... Read more

December 12, 2014December 12, 2014

Study Correlates Obesity and Cancer Incidence

According to a group of researchers from The University of Queensland, Australia, increased obesity levels are aggravating the problem of cancer worldwide. The study, titled “Global burden of cancer attributable ... Read more

December 11, 2014December 11, 2014

Study Finds Combination Therapy Efficient Against Colorectal Cancer

A recent study published in the journal PLos One found important genetic signalling pathways that may inhibit colorectal cancer (CRC) tumour proliferation. The study entitled “Dual Pharmacological Targeting of the MAP ... Read more

December 10, 2014December 10, 2014

Carcinoma-Associated Fibroblasts And Cancer Cells May Cooperate, According to Study

Researchers from the Institut Curie, Paris, suggest that carcinoma-associated fibroblasts (CAF) and cancer cells may cooperate in the process of cancer invasion. Their work, based on colon cancer cells, will ... Read more

December 9, 2014December 9, 2014

Study Finds Osteoporosis Drugs Could Prevent Colon Cancer Progression

Two recent studies that found bisphosphonates may be a feasible treatment for lung, breast and colon cancers were published this week in the Proceedings of the National Academy of Sciences (PNAS). ... Read more

December 8, 2014December 8, 2014

GI View Receives FDA Clearance For Its Colorectal Cancer Screening System

GI View Ltd., an Israel based company committed to develop and advance the efficacy, precision and comfort of colorectal cancer screening, has received a U.S. Food and Drug Administration (FDA) ... Read more

December 5, 2014

Study Finds Natural and Semisynthetic Compounds Can Inhibit Colon Cancer Proliferation

In a study published in Clinical And Translational Oncology, titled “A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products”, a research team from ... Read more

December 4, 2014

Researchers Design Innovative “Tumor in a Dish” To Test Anti-Cancer Drugs

Researchers from Cancer Prevention and Control at The University of Kansas Cancer Center have found a way to test investigational cancer drugs using an innovative in vitro “tumor in a ... Read more

December 3, 2014December 3, 2014

Study Finds Antacid Could Be Used For Colorectal Cancer Treatment

In a recent article titled “Repurposing drugs in oncology (ReDO)—Cimetidine as an anti-cancer agent”, published in the ecancermedicalscience journal, a team of researchers discussed the benefits of cimetidine, a commonly ... Read more

December 2, 2014

Colon Cancer Vaccine Research Funded By The Susan Cohan Colon Cancer Foundation And The Zhang Family

The Susan Cohan Colon Cancer Foundation along with the Zhang family will fund the research of an innovative colon cancer vaccine to be developed at the Sidney Kimmel Comprehensive Cancer ... Read more

December 1, 2014December 1, 2014

Carnegie Hill Endoscopy Will Have An Open House To Showcase FUSE Technology

The open house celebration for Carnegie Hill Endoscopy (CHE), situated in New York’s Upper East Side, will occur on December 4, 2014. This advanced medical facility is a collaborative project with Beth ... Read more

November 25, 2014November 25, 2014

Four Genes Used to Predict Rectal Cancer Patient Response to CRT

Identifying a certain subset of genes in individuals with locally advanced rectal cancer (LARC) could be useful in determining the most cost- and time-effective treatment options for patients, according to ... Read more

November 24, 2014November 24, 2014

Trovagene Reveals Results of Clinical Study for Detection of KRAS Mutations In Colorectal Cancer Patients

Trovagene, Inc., has announced the results of its clinical study evaluating the capacity of the company’s Precision Cancer Monitoring technology to detect and quantify KRAS mutations in the blood and urine ... Read more

November 21, 2014November 21, 2014

Study Finds Malaria Drug Could Aid In Colorectal Cancer Treatment

Researchers at St George’s, University of London, have developed a pilot study where they found artesunate, a common malaria drug, may aid in the treatment of colorectal cancer (CRC), and ... Read more

November 20, 2014November 20, 2014

Study Finds Financial Incentive Can Encourage Patients to Complete Colon Cancer Screening

A recent study titled “Financial Incentives for Completion of Fecal Occult Blood Tests among Veterans: A 2-Stage Pragmatic Cluster Randomized, Controlled Trial”, published in the journal Annals of Internal Medicine, showed ... Read more

November 19, 2014

PolypDx Recognized by Frost & Sullivan As A Screening Test for Early Detection of Colorectal Cancer

Frost & Sullivan, has preformed an analysis of the metabolomics-based diagnostic test market and recognized Metabolomic Technologies Inc. (MTI) with the 2014 North American Frost & Sullivan Award for Technology ... Read more

November 19, 2014November 19, 2014

Study Validates The 12-Gene Colon Cancer Recurrence Score For Prediction of Recurrence Risk in Rectal Cancer Patients

In a recent study titled “Validation of the 12-Gene Colon Cancer Recurrence Score as a Predictor of Recurrence Risk in Stage II and III Rectal Cancer Patients”, published in the ... Read more

November 17, 2014November 17, 2014

Study Finds Link Between Colon Cancer Death Rates And Racial, Ethnic, Socioeconomic And Geographic Disparities

While the third leading cause of cancer-related deaths in the U.S used to affect mostly wealthy, white northerners, this trend has shifted, with the current populations at higher risk being poor, ... Read more

November 14, 2014

Study Finds KRAS Status Can Predict Time To Recurrence In Resected Stage III Colon Cancer

In a recent study titled “Prognostic value of KRAS mutations in stage III colon cancer: post-hoc analysis of the PETACC8 phase III trial dataset”, published in the journal Annals of ... Read more

November 13, 2014

Study Analyzes Healthy Lifestyle In Colorectal Cancer Prevention

A large European multisite study conducted by Krasimira Aleksandrova and colleagues, entitled “Combined impact of healthy lifestyle factors on colorectal cancer: a large European cohort study” was published this week ... Read more

November 12, 2014

Study Finds Calcium Can Help Prevent Colorectal Cancer

In a news release authored by James Meschino, DC, MS, Director of Nutritional Therapies at the Canadian Integrative Cancer Immunotherapies Clinicin Toronto​, the benefits from calcium intake in the prevention of colorectal cancer ... Read more

November 10, 2014November 10, 2014

Lycera Announces RORγ Oral Immunotherapy Efficient Against Colon Cancer Cells

Lycera Corp., a company developing breakthrough oral immune modulators, announced its latest data concerning the anti-tumor activity of synthetic RORγ agonist product candidates, during the Society for Immunotherapy of Cancer (SITC) ... Read more

November 7, 2014November 7, 2014

Study Finds TET1 Linked To Early Events In Colon Cancer Development

Results of a recent study titled “TET1 is a tumour suppressor that inhibits colon cancer growth by derepressing inhibitors of the WNT pathway” and published in the Oncogene journal, have shown ... Read more

November 6, 2014November 7, 2014

Study Finds Increased Incidence of Colorectal Cancer in Younger Patients

University of Texas MD Anderson Cancer Center researchers have published their latest results  “Increasing Disparities in the Age-Related Incidences of Colon and Rectal Cancers in the United States, 1975-2010” in ... Read more

November 5, 2014November 5, 2014

Study Finds NSAIDs Can Prevent Colon Cancer

A recent study published in the Proceedings of the National Academy of Sciences, titled “BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal anti-inflammatory drugs”, has ... Read more

November 4, 2014November 4, 2014

Study Shows S-1 Adjuvant Chemotherapy Efficiency in Colon Cancer Treatment

In a recent study titled “S-1 as adjuvant chemotherapy for stage III colon cancer: a randomized phase III study (ACTS-CC trial)”, published in the Annals of Oncology, Dr. Yoshida and colleagues at the Cancer Chemotherapy Center, Osaka Medical College Hospital, Osaka, Japan, designed a ... Read more

November 3, 2014

New Data Supports Efficacy of Fuse Endoscopy System In Colorectal Cancer Diagnosis

EndoChoice, a company focusing on manufacturing specialized endoscopic imaging, has announced its latest study results confirming the efficacy of the Fuse Full Spectrum Endoscopy System at the American College of ... Read more

October 31, 2014October 31, 2014

Study Finds Protein Complex Slows Colon Cancer Tumor Growth

In a recent study titled “A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth” published in the Molecular Cell journal, ... Read more

October 30, 2014October 30, 2014

Study Finds Mutation In Colorectal Cancers May Increase Susceptibility to New Cancer Drugs

A study titled “RNF43 is frequently mutated in colorectal and endometrial cancers” and published in Nature Genetics found a new gene, RNF43 that is frequently mutated in colorectal adenocarcinomas and ... Read more

October 29, 2014

Study Finds Sphingolipids As Key Link Between Diet, Inflammation And Cancer

In a recent study titled “Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs”, published in The Journal of Clinical Investigation, a team of researchers from the Children’s Hospital Oakland ... Read more

October 28, 2014October 28, 2014

Colon Cancer Patients May Benefit From Prehabilitation Before Surgery

A new study entitled “Prehabilitation versus Rehabilitation: A Randomized Control Trial in Patients Undergoing Colorectal Resection for Cancer” suggests that a prehabilitition program including exercise, healthy diet and relaxation techniques ... Read more

October 27, 2014October 27, 2014

Study Finds Mechanism Involved in Diagnosis And Targeted Therapy of Colorectal Cancer

In a recent study published in Cancer Cell titled “Rab1A Is an mTORC1 Activator and a Colorectal Oncogene”, a team of researchers from the Rutgers Cancer Institute, New Jersey, has ... Read more

October 24, 2014October 24, 2014

Taiho’s Investigational Colorectal Cancer Drug Receives FDA Fast Track Designation

The U.S. Food and Drug Administration (FDA) has granted Fast Track designation for Taiho Oncology’s TAS-102 (trifluridine/tipiracil hydrochloride) for the treatment of refractory metastatic colorectal cancer (mCRC). The Fast Track ... Read more

October 23, 2014October 23, 2014

Phase 3 Study on Metastatic Colorectal Cancer Enrolls First Patient

A new global Phase 3 clinical study to treat patients with metastatic colorectal cancer (mCRC), has enrolled its first patient, as announced Boehringer Ingelheim Pharmaceuticals Inc. (BI). Colorectal cancer is the third ... Read more

October 23, 2014October 23, 2014

Genetic Tests in Population Leave Colorectal Cancer Screening Rates Unchanged

An “excellent” study–defined as such by meeting the randomized controlled trial requirement of Level I Evidence in medicine–from the Fox Chase Cancer Center and Jefferson Medical College in Pennsylvania and ... Read more

October 21, 2014October 21, 2014

Oratecan Shows Promise in Phase I Clinical Trial for Colon Cancer

 Hanmi Pharmaceuticals and Kinex Pharmaceuticals recently announced preliminary findings from a Phase I clinical trial of Oratecan, an oral formulation of irinotecan (Camptosar), an already-approved intravenous treatment for colon cancer. The oral ... Read more

October 20, 2014October 20, 2014

Kaiser Permanente Aims to Reduce 50% of Colorectal Cancer Deaths

During the American Society of Clinical Oncology Quality Care Symposium, in Boston, health provider Kaiser Permanente Southern California announced its focus in reducing the number of colorectal cancer-related deaths by half, until 2023. In order to ... Read more

October 17, 2014October 17, 2014

Colon Cancer Suppressor Gene SIRT6 Promotes Skin Cancer

Researchers from The University of Chicago have published their recent findings in The Journal of Cancer Research, titled “SIRT6 Promotes COX-2 Expression and Acts as an Oncogene in Skin Cancer”, whereby ... Read more

October 16, 2014October 16, 2014

New ESMO Guidelines Recommend SIR-Spheres y-90 Resin Microspheres For Metastatic Colorectal Cancer Treatment

The new European Society for Medical Oncology (ESMO) clinical guidelines for the treatment of metastatic colorectal cancer (mCRC) were recently published in the September issue of the Annals of Oncology Journal. These ... Read more

October 15, 2014October 15, 2014

Oral Biological Drug Can Reduce Precancerous Polyp Formation In Colon

A group of researchers from the University at Buffalo School of Medicine and Biomedical Sciences, have published their latest results “Oral Interleukin-10 Alleviates Polyposis via Neutralization of Pathogenic T-Regulatory Cells” ... Read more

October 15, 2014October 15, 2014

EpHA2 Protein Linked to Poor Colorectal Cancer Prognosis

Clinicians may be able to use another prognostic marker for colon cancer in order to make decisions for the best treatment option for their patients. A new study from Queen’s ... Read more

October 14, 2014

Replacing Guanylin Hormone Can Prevent Colon Cancer Development

Researchers from the Thomas Jefferson University have recently published a study in the Cancer, Epidemiology, Biomarkers & Prevention journal  titled “The Paracrine Hormone for the GUCY2C Tumor Suppressor, Guanylin, Is Universally Lost in Colorectal ... Read more

October 13, 2014October 13, 2014

Simple Yogurt Based Test for Colon Cancer Developing at MIT

A group of researchers at the MIT is engineering yogurt bacteria to detect colorectal cancer and other diseases in a non-invasive and simple way. The team, led by Sangeeta Bhatia, PhD, a ... Read more

October 10, 2014

Study Finds Non-Fiber Laxatives Might Influence Colon Cancer Risk

Recent results from a study titled “A Prospective Study of the Effect of Bowel Movement Frequency, Constipation, and Laxative Use on Colorectal Cancer Risk”, published in the American Journal of Gastroenterology, ... Read more

October 9, 2014October 9, 2014

Two Studies Evaluating anti-EGFR And anti-VEGF Treatments in Metastatic Colorectal Cancer Presented At ESMO

During the European Society for Medical Oncology Meeting (ESMO) 2014, in Madrid, Spain, the results from two different studies evaluating the use of anti-EGFR or anti-VEGF treatments in first-line RAS ... Read more

October 8, 2014October 8, 2014

Study Finds Different Access to Laparoscopic Colectomy Depending on Geographic Region

In a new study titled “Geographic Variation in Use of Laparoscopic Colectomy for Colon Cancer” published in the Journal of Clinical Oncology, researchers from the University of Michigan Comprehensive Cancer ... Read more

October 7, 2014October 7, 2014

Obesity Increases Risk of Second Cancer In Colorectal Cancer Survivors

A new study entitled “Body Mass Index and Risk of Second Obesity-Associated Cancers After Colorectal Cancer: A Pooled Analysis of Prospective Cohort Studies” published in the September issue of Journal ... Read more

October 7, 2014October 7, 2014

Clinically Relevant JAK Inhibitors Battle Colon Cancer in Pre-Clinical Studies

An effective new therapy used against bowel cancer tumors may be quickly propelled from laboratory testing to clinical trials for subsequent approval. The therapy, already in use to treat psoriasis, arthritis, ... Read more

October 3, 2014

Researchers Find microRNAs Linked to Colon Cancer Tumor Growth

Researchers from the University of Minnesota have published an article titled “Sequential expression of miR-182 and miR-503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma” ... Read more

October 2, 2014October 2, 2014

Researchers Develop New Colon Cancer Peptide Vaccines And Inhibitors

Two recent studies titled “IGF-1R Peptide Vaccines/Mimics Inhibit the Growth of BxPC3 and JIMT-1 Cancer Cells in vitro and in vivo and Combined Therapy with HER-1 and HER-2 Peptides Induces ... Read more

October 1, 2014October 1, 2014

Benefits of Colorectal Cancer Screening Evaluated in French Studies

As suggested by a study presented at the ESMO 2014 Congress, biennial colorectal screening initiatives may increase the rate of high risk pre-cancerous adenomas diagnosis by nearly 90%. In Côte-d’Or, ... Read more

September 30, 2014September 30, 2014

Obesity and Inflammation In Adolescence Linked to Colon Cancer Later

A study presented at the American Association for Cancer Research’s International Conference on Frontiers in Cancer Prevention Research, held in New Orleans, has shown that obesity and inflammation in late ... Read more

September 29, 2014September 29, 2014

Colon Cancer Research Wins Grant for Oncology Innovation Award From EDM Serono

Among the winners of the first Grant for Oncology Innovation (GOI), awarded by EMD Serono, a biopharmaceutical division of Merck KGaA, were two research projects focused on colon cancer therapy. ... Read more

September 26, 2014September 26, 2014

Colon Cancer Alliance Launches “Screen This Too!” Awareness Campaign in October

The Colon Cancer Alliance is concerned that women are not being as preventive with colon cancer as they are with breast cancer. In response, they are launching a campaign called Screen ... Read more

September 25, 2014September 25, 2014

Novel Colorectal Cancer Screening Test Gaining Traction in Health Plans

The molecular diagnostics company Exact Sciences Corporation announced that their non-profit cooperative, health plan Group Health Cooperative, is going to become the first in Wisconsin to provide access to a noninvasive stool ... Read more

September 24, 2014September 24, 2014

Researchers Uncover Cancer Drug Target That Utilizes Lipid Chemical Messengers

A new study, entitled “TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer” published on Cancer Cell by first author Dr. Svetlana Fayngerts from Dr. Youhai Chen’s group, ... Read more

September 22, 2014September 22, 2014

Risk of Death from Colon Cancer Lower Among Those with Intestinal Polyps

A team of researchers from the University of Oslo have published a study entitled “Long-Term Colorectal-Cancer Mortality after Adenoma Removal,” in The New England Journal of Medicine, where they demonstrated that patients ... Read more

September 19, 2014September 19, 2014

Cassava Leaves, Roots Show Promise Against Colon Cancer

Cassava, or Manihot esculenta, belongs to the family Euphorbiaceae and is cultivated in tropical and subtropical regions for its edible starchy tuberous root, which is commonly dried into a powder and named tapioca. In a ... Read more

September 18, 2014September 18, 2014

How to Create a Healthy Colon Cancer Preventive Diet

Colon cancer is a malignant tumor afflicting any of the five parts of the colon, which are the ascending colon, transverse colon, descending colon, sigmoid colon, and the rectum, all parts of ... Read more

September 17, 2014

Health Economic Analysis Suggests Oncotype DX Colon Cancer Test May Improve Direct Medical Costs And Patient Quality Of Life

The Oncotype® DX colon cancer test can significantly reduce direct medical costs and improve patient quality of life by helping avoid side effects of unnecessary treatment, according to a PharmacoEconomics journal health ... Read more

September 16, 2014September 16, 2014

Colorectal Cancer Drug Significantly Improves Overall Survival

Eli Lilly and Company has announced that the RAISE trial, a Phase III study of ramucirumab (CYRAMZA™) in combination with chemotherapy in patients with metastatic colorectal cancer (mCRC), met its ... Read more

September 15, 2014September 15, 2014

Genomic Health’s Oncotype DX Colon Cancer Test Proven Cost-Effective by Mayo Clinic Study

Genomic Health, a provider of genomic-based diagnostic tests for treatment of early stage cancer, revealed positive results of a health economic study that demonstrates the direct reduction of medical costs and improvement of ... Read more

September 12, 2014September 12, 2014

XBiotech Halts Fast-Track Antibody Cancer Therapy Study; Reports Positive Phase III Results

Austin, Texas based biotechnology firm XBiotech U.S.A. Inc. has announced interim results from its fast-tracked Phase III study being conducted in the US for its anti-cancer agent Xilonix. A True ... Read more

September 11, 2014September 11, 2014

Study Analyzes Spatial Variation of Cancer in the Gut

Even though the small intestine has a greater cell mass than the colon, it is longer, has a greater surface area and a faster rate of epithelial turnover, the incidence ... Read more

September 11, 2014September 11, 2014

Task Force Recommends Newly Diagnosed Colorectal Cancer Patients Get Genetic Tumor Tests

Newly diagnosed colorectal cancer patients are recommended to partake in genetic testing of their tumors by the U.S. Multi-Society Task Force on Colorectal Cancer, which recently compiled a new guideline for ... Read more

September 9, 2014September 9, 2014

Immunotoxins May Be Useful As a Colon Cancer Therapy

Immunotoxins, antibodies targeted towards deadly toxins, have been a central focus of research to find immunotherapies for cancer. However, results have been disappointing so far, partly because cancer and normal ... Read more

September 8, 2014September 8, 2014

Researchers Developing New User-Friendly Colorectal Cancer Test

Researchers from McMaster University in Hamilton, Canada, are developing a simple, non-invasive test for colorectal cancer, to ultimately increase the number of people screened for this type of cancer. “I ... Read more

September 5, 2014September 5, 2014

Prediction Model Estimates Time of Colorectal Cancer Patient Survival

“How long do I have, doctor?” is a question on the minds of many patients diagnosed with metastatic colorectal cancer. In light of a new study published in Annals of Oncology entitled ... Read more

September 4, 2014September 4, 2014

APC Protein Plays Role in Suppressing Colorectal Cancer, According to Study

Researchers from the University of Kansas have uncovered a new role for the protein adenomatous polyposis coli (APC) in suppressing colorectal cancer (CRC). Functional loss of the APC protein is thought ... Read more

September 3, 2014September 3, 2014

Vaccinogen’s OncoVAX Enters Phase IIIb Clinical Trial for Stage 2 Colon Cancer

Vaccinogen, a cancer vaccine company, will begin ACTIVE, a confirmatory Phase IIIb pivotal study of the company’s vaccine OncoVax ®, in patients with resectable Stage 2 colon cancer, under a U.S. Food ... Read more

September 2, 2014September 2, 2014

DNA-based Noninvasive Colorectal Cancer Screening Test Approved by FDA

Texas based Exact Sciences Corp. announced that the U.S. Food and Drug Administration (FDA) has approved Cologuard, the company’s noninvasive, stool DNA colorectal cancer screening test. Furthermore, it also received a proposed coverage memorandum ... Read more

August 29, 2014August 30, 2014

Experimental Therapy Showing Promise in Studies For Subset of Stage III Colon Cancer Patients

Researchers from the University of Washington have found that irinotecan-based therapy, a topoisomerase 1 inhibitor, can improve survival rates in a subset of patients with stage III colon cancer. In ... Read more

August 28, 2014August 30, 2014

Colon Cancer Risk Mitigated by Sigmoidoscopy in Ten-Year Study

Sigmoidoscopy, a medical procedure analogous to a less invasive colonoscopy, can cut the risk for developing or dying from colon cancer. The finding, published in the Journal of the American Medical ... Read more