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An international research team led by Timothy C. Wang from Columbia University identified a new cancer-initiating stem cell population in the colon and intestine. The study entitled “Krt19+/Lgr5– Cells Are ... Read more

June 22, 2015June 22, 2015

Genetic Test May Improve Patient’s Response to Metastatic Colorectal Cancer Treatment

A research team from the University of California San Diego identified biomarkers that may predict the response of metastatic colorectal cancer (mCRC) patients to chemotherapy. The results entitled “ERCC1 and TS ... Read more

May 1, 2015May 1, 2015

FDA Approves New Monoclonal Antibody For Colon Cancer Treatment

The U. S. Food and Drug Administration (FDA) has recently approved a new drug for colon cancer. According to an announcement on the FDA website, the approval has been granted for ... Read more

April 22, 2015April 22, 2015

A New Cold Plasma Apparatus To Kill Cancer Cells In Colon Cancer

A new cold plasma device, Canady Helios Cold Plasma Scalp, developed by the US Medical Innovations (USMI) family of companies, was used in a patient diagnosed with inoperable colon cancer. The ... Read more

February 19, 2015February 19, 2015

Combination of BRAF Inhibitors Might Improve Colorectal Cancer Treatment

A research team at Albert-Ludwigs-University in Germany led by Dr. Tilman Brummer studied the role of BRAF mutations in metastasis of colorectal carcinoma using a three-dimensional (3D) tissue culture model. The ... Read more

February 4, 2015February 4, 2015

Cytotoxic T Cells Indicate Favorable Prognosis in Colorectal Cancer

A research team from Heidelberg and Dresden has found a connection between increased levels of TNF alpha in tumor tissue and an increased number of activated cytotoxic T cells that ... Read more

February 2, 2015February 2, 2015

MicroRNA Biomarkers To Identify Colon Cancer Metastases

A recent study published in the Journal of the National Cancer Institute by Baylor Research Institute investigators has identified novel metastasis-specific microRNA signatures in samples of primary colorectal cancers that ... Read more

January 30, 2015January 30, 2015

High-Quality Cancer Care Erases Racial Disparities in Colon Cancer Survival,

A recent study published in the Journal of Clinical Oncology has demonstrated that the gap between African-American colon cancer patients’ survival and white patients can be reduced upon the delivery ... Read more

January 29, 2015January 29, 2015

Colorectal Cancer Metastasis Associated With Liver Metabolic Processes

Recent findings published in Cell by Rockefeller researchers have shown that metabolic processes occurring during liver metastasis of colorectal cancer can be crucial to activate starving transient cancer cells, allowing ... Read more

January 27, 2015January 27, 2015

Hypertension and Proteinuria in Bevacizumab-Treated Metastatic Colorectal Cancer Patients

In a recent study titled “Correlation of Hypertension and Proteinuria with Outcome in Elderly Bevacizumab-Treated Patients with Metastatic Colorectal Cancer”, published in PlosOne, a team of Spanish researchers designed a ... Read more

January 22, 2015

Trovagene Presented Clinical Result From Its Precision Cancer Monitoring Platform in Colorectal Cancer Patients

Trovagene, Inc., has presented the results of a clinical study during the 2015 Gastrointestinal Cancer Symposium held in San Francisco, CA, showing the efficacy of the company’s Precision Cancer Monitoring platform in ... Read more

January 21, 2015January 21, 2015

Study Finds Link Between Colon Cancer And Sedentary Habits

According to a new study published in the Annals of Internal Medicine by Canadian researchers, there is a serious risk of illness or even premature death from too much sitting ... Read more

January 20, 2015January 20, 2015

Gene Involved In Colon Cancer Progression and Chemoresistance Identified

Researchers from Shanghai Jiao Tong University, China, have identified p21-Activated kinase 6 (PAK6) as a predictor of 5-fluorouracil (5-FU) treatment response in colon cancer. Even though surgery is usually preformed ... Read more

January 19, 2015January 19, 2015

Vitamin D Can Enhance The Immune System, Protecting Against Colorectal Cancer

According to new research by Dana-Farber Cancer Institute investigators, vitamin D can exert a protective effect against colorectal cancer by enhancing the immune system’s capacity to detect cancer cells. The ... Read more

January 15, 2015January 15, 2015

High Vitamin D Levels Increase Survival of Metastatic Colorectal Cancer Patients

A recent study, presented during the 2015 American Society of Cancer Oncology (ASCO) Gastrointestinal Cancers Symposium, San Francisco, has shown that metastatic colorectal cancer (mCRC) patients who had high levels ... Read more

January 14, 2015January 14, 2015

New Colorectal Cancer Gene Mutations in African American Patients Indentified

A team of researchers has identified new genetic mutations specific for colon cancer in African Americans, one of the populations with a higher incidence of this malignancy. The study, published ... Read more

January 13, 2015January 13, 2015

Chemoradiation Treatment Improves Overall Survival Rates for Rectal Cancer Patients

A recent study published in the International Journal of Radiation Oncology • Biology • Physics (Red Journal) has demonstrated that patients suffering from locally advanced rectal cancer who are treated with preoperative ... Read more

January 9, 2015January 9, 2015

Seven New KRAS Mutations Found In Colorectal Cancer

In a recent study titled “Novel KRAS Gene Mutations in Sporadic Colorectal Cancer” published in the PlosOne journal, an international team of researchers has reported seven new KRAS gene mutations ... Read more

January 8, 2015January 8, 2015

Healthy Dietary Habits May Lower Risk of Obesity-Related Cancers

A new study led by New York University researchers shows that a diet with low alcohol intake and with a high plant intake can help to reduce the risk of ... Read more

January 6, 2015

Researchers Review TRK Cancer Mutations As Targets In New Clinical Trials

A recent study published in the journal Cancer Discovery reviewed several clinical trials that are using drugs targeting the TRK gene for the treatment of different types of cancer, including ... Read more

January 5, 2015January 5, 2015

Taiho Oncology Submits New Drug Application To The FDA for Treatment of Refractory Metastatic Colorectal Cancer

Taiho Oncology, Inc. has finalized its New Drug Application (NDA) submission to the U.S. Food and Drug Administration (FDA) for its proprietary TAS-102 (trifluridine and tipiracil hydrochloride) for the treatment ... Read more

January 2, 2015January 2, 2015

Adiponectin Polymorphisms Are Linked To Colorectal Cancer Risk

In a recent study titled “Association Between Adiponectin Polymorphisms and the Risk of Colorectal Cancer”, published in Genetic Testing and Molecular Biomarkers, a team of researchers from Harbin Medical University, ... Read more

December 30, 2014December 30, 2014

Researchers Develop And Test A Novel Screening Kit for Colorectal Cancer

In a new study titled “The Usefulness of a Novel Screening Kit for Colorectal Cancer Using the Immunochromatographic Fecal Tumor M2 Pyruvate Kinase Test “, published in the Gut and ... Read more

December 29, 2014December 29, 2014

Researchers Find Genetic Determinants of Colorectal Cancer And Other Disorders

Researchers from the University of Toronto have developed a new computational technique that is able to pinpoint DNA mutations that can cause disease. The study, published in Science, reports on ... Read more

December 23, 2014December 26, 2014

Can Inflammation Causing Intestinal Bacteria Be Inherited?

A team of researchers from the University of Minnesota, along with international collaborators, has found that intestinal bacteria responsible for Crohn’s disease and ulcerative colitis (known as inflammatory bowel disease ... Read more

December 22, 2014December 22, 2014

Study Finds Link Between Selenium And Colorectal Cancer

A recent study published in the International Journal of Cancer by Newcastle University researchers found that high levels of selenium are correlated with a lower risk of colorectal cancer. The ... Read more

December 19, 2014December 19, 2014

New Therapy Shows Promise In Colorectal Cancer Treatment

A team at Roswell Park Cancer Institute (RPCI) has published the results of a recent study in the Cancer Research journal, where they show that novel anticancer agent FL118 can ... Read more

December 18, 2014December 18, 2014

Bacterial Biofilms Linked To Colon Cancer, According To Researchers

A recent study titled “Microbiota organization is a distinct feature of proximal colorectal cancers”, published in the Proceedings of the National Academy of Sciences (PNAS), has found that bacterial biofilms ... Read more

December 17, 2014December 17, 2014

Study Finds TV Time Negatively Associated With Colorectal Cancer Survival

A recent study titled “Pre- and Postdiagnosis Physical Activity,Television Viewing, and Mortality Among Patients With Colorectal Cancer in the National Institutes of Health–AARP Diet and Health Study”, published in the Journal ... Read more

December 16, 2014December 16, 2014

Study Finds Hormone Loss Could Lead To Colon Cancer Progression

In a recent study published in the Cancer, Epidemiology, Biomarkers & Prevention journal, a team of researchers from Thomas Jefferson University showed that upon the loss of an essential hormone, ... Read more

December 15, 2014December 15, 2014

Study Finds Evidence For Testosterone Role in Colon Cancer Development

In a recent study titled “Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones”, published in the Proceedings of the National Academy of Sciences ... Read more

December 12, 2014December 12, 2014

Study Correlates Obesity and Cancer Incidence

According to a group of researchers from The University of Queensland, Australia, increased obesity levels are aggravating the problem of cancer worldwide. The study, titled “Global burden of cancer attributable ... Read more

December 8, 2014December 8, 2014

GI View Receives FDA Clearance For Its Colorectal Cancer Screening System

GI View Ltd., an Israel based company committed to develop and advance the efficacy, precision and comfort of colorectal cancer screening, has received a U.S. Food and Drug Administration (FDA) ... Read more

December 5, 2014

Study Finds Natural and Semisynthetic Compounds Can Inhibit Colon Cancer Proliferation

In a study published in Clinical And Translational Oncology, titled “A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products”, a research team from ... Read more

December 4, 2014

Researchers Design Innovative “Tumor in a Dish” To Test Anti-Cancer Drugs

Researchers from Cancer Prevention and Control at The University of Kansas Cancer Center have found a way to test investigational cancer drugs using an innovative in vitro “tumor in a ... Read more

December 3, 2014December 3, 2014

Study Finds Antacid Could Be Used For Colorectal Cancer Treatment

In a recent article titled “Repurposing drugs in oncology (ReDO)—Cimetidine as an anti-cancer agent”, published in the ecancermedicalscience journal, a team of researchers discussed the benefits of cimetidine, a commonly ... Read more

December 2, 2014

Colon Cancer Vaccine Research Funded By The Susan Cohan Colon Cancer Foundation And The Zhang Family

The Susan Cohan Colon Cancer Foundation along with the Zhang family will fund the research of an innovative colon cancer vaccine to be developed at the Sidney Kimmel Comprehensive Cancer ... Read more

December 1, 2014December 1, 2014

Carnegie Hill Endoscopy Will Have An Open House To Showcase FUSE Technology

The open house celebration for Carnegie Hill Endoscopy (CHE), situated in New York’s Upper East Side, will occur on December 4, 2014. This advanced medical facility is a collaborative project with Beth ... Read more

November 24, 2014November 24, 2014

Trovagene Reveals Results of Clinical Study for Detection of KRAS Mutations In Colorectal Cancer Patients

Trovagene, Inc., has announced the results of its clinical study evaluating the capacity of the company’s Precision Cancer Monitoring technology to detect and quantify KRAS mutations in the blood and urine ... Read more

November 21, 2014November 21, 2014

Study Finds Malaria Drug Could Aid In Colorectal Cancer Treatment

Researchers at St George’s, University of London, have developed a pilot study where they found artesunate, a common malaria drug, may aid in the treatment of colorectal cancer (CRC), and ... Read more

November 20, 2014November 20, 2014

Study Finds Financial Incentive Can Encourage Patients to Complete Colon Cancer Screening

A recent study titled “Financial Incentives for Completion of Fecal Occult Blood Tests among Veterans: A 2-Stage Pragmatic Cluster Randomized, Controlled Trial”, published in the journal Annals of Internal Medicine, showed ... Read more

November 19, 2014

PolypDx Recognized by Frost & Sullivan As A Screening Test for Early Detection of Colorectal Cancer

Frost & Sullivan, has preformed an analysis of the metabolomics-based diagnostic test market and recognized Metabolomic Technologies Inc. (MTI) with the 2014 North American Frost & Sullivan Award for Technology ... Read more

November 19, 2014November 19, 2014

Study Validates The 12-Gene Colon Cancer Recurrence Score For Prediction of Recurrence Risk in Rectal Cancer Patients

In a recent study titled “Validation of the 12-Gene Colon Cancer Recurrence Score as a Predictor of Recurrence Risk in Stage II and III Rectal Cancer Patients”, published in the ... Read more

November 17, 2014November 17, 2014

Study Finds Link Between Colon Cancer Death Rates And Racial, Ethnic, Socioeconomic And Geographic Disparities

While the third leading cause of cancer-related deaths in the U.S used to affect mostly wealthy, white northerners, this trend has shifted, with the current populations at higher risk being poor, ... Read more

November 14, 2014

Study Finds KRAS Status Can Predict Time To Recurrence In Resected Stage III Colon Cancer

In a recent study titled “Prognostic value of KRAS mutations in stage III colon cancer: post-hoc analysis of the PETACC8 phase III trial dataset”, published in the journal Annals of ... Read more

November 10, 2014November 10, 2014

Lycera Announces RORγ Oral Immunotherapy Efficient Against Colon Cancer Cells

Lycera Corp., a company developing breakthrough oral immune modulators, announced its latest data concerning the anti-tumor activity of synthetic RORγ agonist product candidates, during the Society for Immunotherapy of Cancer (SITC) ... Read more

November 7, 2014November 7, 2014

Study Finds TET1 Linked To Early Events In Colon Cancer Development

Results of a recent study titled “TET1 is a tumour suppressor that inhibits colon cancer growth by derepressing inhibitors of the WNT pathway” and published in the Oncogene journal, have shown ... Read more

November 6, 2014November 7, 2014

Study Finds Increased Incidence of Colorectal Cancer in Younger Patients

University of Texas MD Anderson Cancer Center researchers have published their latest results “Increasing Disparities in the Age-Related Incidences of Colon and Rectal Cancers in the United States, 1975-2010” in ... Read more

November 5, 2014November 5, 2014

Study Finds NSAIDs Can Prevent Colon Cancer

A recent study published in the Proceedings of the National Academy of Sciences, titled “BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal anti-inflammatory drugs”, has ... Read more

November 4, 2014November 4, 2014

Study Shows S-1 Adjuvant Chemotherapy Efficiency in Colon Cancer Treatment

In a recent study titled “S-1 as adjuvant chemotherapy for stage III colon cancer: a randomized phase III study (ACTS-CC trial)”, published in the Annals of Oncology, Dr. Yoshida and colleagues at the Cancer Chemotherapy Center, Osaka Medical College Hospital, Osaka, Japan, designed a ... Read more

November 3, 2014

New Data Supports Efficacy of Fuse Endoscopy System In Colorectal Cancer Diagnosis

EndoChoice, a company focusing on manufacturing specialized endoscopic imaging, has announced its latest study results confirming the efficacy of the Fuse Full Spectrum Endoscopy System at the American College of ... Read more

October 31, 2014October 31, 2014

Study Finds Protein Complex Slows Colon Cancer Tumor Growth

In a recent study titled “A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth” published in the Molecular Cell journal, ... Read more

October 29, 2014

Study Finds Sphingolipids As Key Link Between Diet, Inflammation And Cancer

In a recent study titled “Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs”, published in The Journal of Clinical Investigation, a team of researchers from the Children’s Hospital Oakland ... Read more

October 27, 2014October 27, 2014

Study Finds Mechanism Involved in Diagnosis And Targeted Therapy of Colorectal Cancer

In a recent study published in Cancer Cell titled “Rab1A Is an mTORC1 Activator and a Colorectal Oncogene”, a team of researchers from the Rutgers Cancer Institute, New Jersey, has ... Read more

October 24, 2014October 24, 2014

Taiho’s Investigational Colorectal Cancer Drug Receives FDA Fast Track Designation

The U.S. Food and Drug Administration (FDA) has granted Fast Track designation for Taiho Oncology’s TAS-102 (trifluridine/tipiracil hydrochloride) for the treatment of refractory metastatic colorectal cancer (mCRC). The Fast Track ... Read more

October 17, 2014October 17, 2014

Colon Cancer Suppressor Gene SIRT6 Promotes Skin Cancer

Researchers from The University of Chicago have published their recent findings in The Journal of Cancer Research, titled “SIRT6 Promotes COX-2 Expression and Acts as an Oncogene in Skin Cancer”, whereby ... Read more

October 15, 2014October 15, 2014

Oral Biological Drug Can Reduce Precancerous Polyp Formation In Colon

A group of researchers from the University at Buffalo School of Medicine and Biomedical Sciences, have published their latest results “Oral Interleukin-10 Alleviates Polyposis via Neutralization of Pathogenic T-Regulatory Cells” ... Read more

October 13, 2014October 13, 2014

Simple Yogurt Based Test for Colon Cancer Developing at MIT

A group of researchers at the MIT is engineering yogurt bacteria to detect colorectal cancer and other diseases in a non-invasive and simple way. The team, led by Sangeeta Bhatia, PhD, a ... Read more

October 10, 2014

Study Finds Non-Fiber Laxatives Might Influence Colon Cancer Risk

Recent results from a study titled “A Prospective Study of the Effect of Bowel Movement Frequency, Constipation, and Laxative Use on Colorectal Cancer Risk”, published in the American Journal of Gastroenterology, ... Read more

October 9, 2014October 9, 2014

Two Studies Evaluating anti-EGFR And anti-VEGF Treatments in Metastatic Colorectal Cancer Presented At ESMO

During the European Society for Medical Oncology Meeting (ESMO) 2014, in Madrid, Spain, the results from two different studies evaluating the use of anti-EGFR or anti-VEGF treatments in first-line RAS ... Read more

October 8, 2014October 8, 2014

Study Finds Different Access to Laparoscopic Colectomy Depending on Geographic Region

In a new study titled “Geographic Variation in Use of Laparoscopic Colectomy for Colon Cancer” published in the Journal of Clinical Oncology, researchers from the University of Michigan Comprehensive Cancer ... Read more

October 3, 2014

Researchers Find microRNAs Linked to Colon Cancer Tumor Growth

Researchers from the University of Minnesota have published an article titled “Sequential expression of miR-182 and miR-503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma” ... Read more

September 30, 2014September 30, 2014

Obesity and Inflammation In Adolescence Linked to Colon Cancer Later

A study presented at the American Association for Cancer Research’s International Conference on Frontiers in Cancer Prevention Research, held in New Orleans, has shown that obesity and inflammation in late ... Read more

September 29, 2014September 29, 2014

Colon Cancer Research Wins Grant for Oncology Innovation Award From EDM Serono

Among the winners of the first Grant for Oncology Innovation (GOI), awarded by EMD Serono, a biopharmaceutical division of Merck KGaA, were two research projects focused on colon cancer therapy. ... Read more

September 22, 2014September 22, 2014

Risk of Death from Colon Cancer Lower Among Those with Intestinal Polyps

A team of researchers from the University of Oslo have published a study entitled “Long-Term Colorectal-Cancer Mortality after Adenoma Removal,” in The New England Journal of Medicine, where they demonstrated that patients ... Read more

September 19, 2014September 19, 2014

Cassava Leaves, Roots Show Promise Against Colon Cancer

Cassava, or Manihot esculenta, belongs to the family Euphorbiaceae and is cultivated in tropical and subtropical regions for its edible starchy tuberous root, which is commonly dried into a powder and named tapioca. In a ... Read more

September 17, 2014

Health Economic Analysis Suggests Oncotype DX Colon Cancer Test May Improve Direct Medical Costs And Patient Quality Of Life

The Oncotype® DX colon cancer test can significantly reduce direct medical costs and improve patient quality of life by helping avoid side effects of unnecessary treatment, according to a PharmacoEconomics journal health ... Read more

September 16, 2014September 16, 2014

Colorectal Cancer Drug Significantly Improves Overall Survival

Eli Lilly and Company has announced that the RAISE trial, a Phase III study of ramucirumab (CYRAMZA™) in combination with chemotherapy in patients with metastatic colorectal cancer (mCRC), met its ... Read more

September 11, 2014September 11, 2014

Study Analyzes Spatial Variation of Cancer in the Gut

Even though the small intestine has a greater cell mass than the colon, it is longer, has a greater surface area and a faster rate of epithelial turnover, the incidence ... Read more

September 9, 2014September 9, 2014

Immunotoxins May Be Useful As a Colon Cancer Therapy

Immunotoxins, antibodies targeted towards deadly toxins, have been a central focus of research to find immunotherapies for cancer. However, results have been disappointing so far, partly because cancer and normal ... Read more

September 8, 2014September 8, 2014

Researchers Developing New User-Friendly Colorectal Cancer Test

Researchers from McMaster University in Hamilton, Canada, are developing a simple, non-invasive test for colorectal cancer, to ultimately increase the number of people screened for this type of cancer. “I ... Read more

September 4, 2014September 4, 2014

APC Protein Plays Role in Suppressing Colorectal Cancer, According to Study

Researchers from the University of Kansas have uncovered a new role for the protein adenomatous polyposis coli (APC) in suppressing colorectal cancer (CRC). Functional loss of the APC protein is thought ... Read more

September 3, 2014September 3, 2014

Vaccinogen’s OncoVAX Enters Phase IIIb Clinical Trial for Stage 2 Colon Cancer

Vaccinogen, a cancer vaccine company, will begin ACTIVE, a confirmatory Phase IIIb pivotal study of the company’s vaccine OncoVax ®, in patients with resectable Stage 2 colon cancer, under a U.S. Food ... Read more

September 2, 2014September 2, 2014

DNA-based Noninvasive Colorectal Cancer Screening Test Approved by FDA

Texas based Exact Sciences Corp. announced that the U.S. Food and Drug Administration (FDA) has approved Cologuard, the company’s noninvasive, stool DNA colorectal cancer screening test. Furthermore, it also received a proposed coverage memorandum ... Read more

August 29, 2014August 30, 2014

Experimental Therapy Showing Promise in Studies For Subset of Stage III Colon Cancer Patients

Researchers from the University of Washington have found that irinotecan-based therapy, a topoisomerase 1 inhibitor, can improve survival rates in a subset of patients with stage III colon cancer. In ... Read more