June 8, 2017August 24, 2022
Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

The MEK inhibitor Mekinist (trametinib) is to be tested in combination with Opdivo (nivolumab) — or Opdivo plus Yervoy (ipilimumab) — in colorectal cancer ... Read more
June 6, 2017
Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Certain patients who underwent surgery for lymph-node positive colon cancer (stage 3) may require only three months of chemotherapy after surgery ... Read more
June 1, 2017June 1, 2017
Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

The MEK inhibitor binimetinib will soon be tested in combination with Opdivo (nivolumab) plus Yervoy (ipilimumab) in colorectal cancer patients ... Read more
May 30, 2017
PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

Trovagene’s PCM-075 therapy for several blood cancers and solid tumors, including colon cancer, proved safe in a Phase 1 clinical ... Read more
May 25, 2017May 25, 2017
FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Colorectal cancer patients with unresectable or metastatic tumors bearing a genetic feature — microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) — ... Read more
May 23, 2017
Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Overweight boys have a higher risk of developing colon cancer in adulthood, but if they lose the extra pounds by ... Read more
May 18, 2017May 18, 2017
Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Tom Marsilje, who survived stage IV colorectal cancer (CRC), has joined forces with New York-based Fight Colorectal Cancer to help patients search for ... Read more
May 16, 2017
Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

The Colon Cancer Coalition, a nonprofit organization that encourages grassroots efforts to promote colon cancer awareness and screening, is partnering ... Read more
May 11, 2017
Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

A new European project aims to develop an innovative endoscope device that can detect and diagnose colorectal cancer in its early ... Read more
May 9, 2017
Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

People who eat healthy, exercise, and do not smoke are less likely to report a personal history of colorectal cancer ... Read more
May 4, 2017May 4, 2017
RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

Small molecule compounds known as RLR agonists, being developed by Kineta to treat colon cancer, were seen to kill cancer ... Read more
May 2, 2017May 2, 2017
New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research

MIT researchers using the CRISPR-Cas9 genome editing and organoid technology have developed a new mouse model with a cancer that ... Read more

September 6, 2016September 6, 2016

Colorectal Cancer Results When Retinoic Acid Is Lost, an Effect Caused by Inflammation

Retinoic acid, a metabolite derived from vitamin A, protects both mice and humans from developing colorectal cancer, according to the results of a new study that also showed that cancer patients ... Read more

August 2, 2016August 2, 2016

Glycosylation-associated Gene Mutations Discovered as New Targets in Colon Cancer

Though the molecular principles of dysfunctional protein glycosylation and the way its enzymatic mechanism is known to cause tumors in such cancers as colorectal cancer (CRC) is not completely understood, the recent study “Biochemical and functional ... Read more

May 19, 2016May 19, 2016

Burden of Colorectal Cancer Greatest in the Medicare Low-income American population

In the United States. colorectal cancer (CRC) is the second leading cause of death related to cancer. Estimates indicate that 49,190 American individuals will die from CRC in 2016. The burden ... Read more

May 4, 2016May 4, 2016

Colon Cancer Linked in Study to Mutations Caused by Imbalance in DNA Building Blocks

Proper balance among the four DNA building blocks, known as dNTPs, needs to be maintained during cell replication to avoid potential mutations. Now, researchers at Umeå University in Sweden have found that a disruption ... Read more

April 19, 2016April 19, 2016

Gene Variant May Contribute to Increased Colorectal Cancer Risk in African-Americans

Wistar Institute researchers have identified a single variant in an important tumor suppressor gene only found in Africans and African-Americans that might explain disparities in the incidence of certain cancers ... Read more

April 5, 2016April 5, 2016

Mutated Glycosyltransferases Might Contribute to Colon Cancer

Faulty protein glycosylation – a process of protein modification– is a hallmark of several cancer forms. But knowledge of how the complex molecular processes might contribute to cancer is sparse. In ... Read more

March 28, 2016March 28, 2016

For Colon Cancer with Liver Metastisis, Immunotherapy Combined with RFA May Benefit Patients

Researchers at the University of Pittsburgh found that radiofrequency ablation (RFA) combined with an immune checkpoint inhibitor resulted in a stronger antitumor immunity with extended survival in human samples of ... Read more

March 2, 2016March 2, 2016

Colon Cancer Gene Found in 18th Century Hungarian Mummified Tissues

Genetic predisposition to colorectal cancer was recently discovered in an 18th century Hungarian mummy. The findings were published in PLOS ONE journal, titled “Detection of a Tumor Suppressor Gene Variant ... Read more

February 23, 2016February 23, 2016

For National Colon Cancer Awareness Month in March, Here’s How to Get Involved

March was officially established as National Colon Cancer Awareness Month in 2000, and 16 years later, the event has grown to be a rallying point for the colon cancer community. Thousands of members, including ... Read more

February 9, 2016February 9, 2016

Promising Colorectal Cancer Therapy That Targets Cancer Stem Cells Moves Forward With Company’s 3rd Patent

Propanc Health Group Corporation, a Melbourne, Australia-based healthcare company focusing on the development of treatments for pancreatic, ovarian, and colorectal cancer treatments, announced it has filed a third patent on the use of PRP, ... Read more

January 25, 2016January 25, 2016

Molecular Link Between Obesity and Increased Risk of Colon Cancer Uncovered

Thomas Jefferson University researchers have found the molecular connection between obesity and an increased risk of colorectal cancer, while also identifying an FDA-approved drug that could prevent the cancer from developing. ... Read more

January 12, 2016January 29, 2016

Colon Cancer and Immune System’s Response to Tumor Development

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are reporting a key finding about the immune system and how it responds to tumor development, ... Read more

Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research