June 8, 2017August 24, 2022
Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

The MEK inhibitor Mekinist (trametinib) is to be tested in combination with Opdivo (nivolumab) — or Opdivo plus Yervoy (ipilimumab) — in colorectal cancer ... Read more
June 6, 2017
Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Certain patients who underwent surgery for lymph-node positive colon cancer (stage 3) may require only three months of chemotherapy after surgery ... Read more
June 1, 2017June 1, 2017
Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

The MEK inhibitor binimetinib will soon be tested in combination with Opdivo (nivolumab) plus Yervoy (ipilimumab) in colorectal cancer patients ... Read more
May 30, 2017
PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

Trovagene’s PCM-075 therapy for several blood cancers and solid tumors, including colon cancer, proved safe in a Phase 1 clinical ... Read more
May 25, 2017May 25, 2017
FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Colorectal cancer patients with unresectable or metastatic tumors bearing a genetic feature — microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) — ... Read more
May 23, 2017
Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Overweight boys have a higher risk of developing colon cancer in adulthood, but if they lose the extra pounds by ... Read more
May 18, 2017May 18, 2017
Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Tom Marsilje, who survived stage IV colorectal cancer (CRC), has joined forces with New York-based Fight Colorectal Cancer to help patients search for ... Read more
May 16, 2017
Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

The Colon Cancer Coalition, a nonprofit organization that encourages grassroots efforts to promote colon cancer awareness and screening, is partnering ... Read more
May 11, 2017
Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

A new European project aims to develop an innovative endoscope device that can detect and diagnose colorectal cancer in its early ... Read more
May 9, 2017
Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

People who eat healthy, exercise, and do not smoke are less likely to report a personal history of colorectal cancer ... Read more
May 4, 2017May 4, 2017
RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

Small molecule compounds known as RLR agonists, being developed by Kineta to treat colon cancer, were seen to kill cancer ... Read more
May 2, 2017May 2, 2017
New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research

MIT researchers using the CRISPR-Cas9 genome editing and organoid technology have developed a new mouse model with a cancer that ... Read more

January 26, 2017

CaroGen and University of Connecticut Collaborate to Develop Colon Cancer Vaccine

The University of Connecticut and the immunotherapy company CaroGen are collaborating to develop a new vaccine to treat colon cancer patients. The vaccine will use CaroGen’s proprietary technology platform, which relies ... Read more

January 24, 2017

Colon Cancer Diagnoses Increased 8% Under Affordable Care Act, Study Shows

The Affordable Care Act (ACA) was found to be effective in making recommended colorectal cancer screening more affordable and accessible for millions of Americans, according to a new study. The ... Read more

January 19, 2017

‘Collateral Lethality’ Offers New Therapeutic Target for Colon, Other Cancers

During the transformation of cells into a malignant cancerous form, some tumor suppressor genes that are responsible for blocking this process are deleted. At times, this genomic editing process can also ... Read more

January 17, 2017

Colorectal Cancer Cells Able to Use Glutamine to Survive, Study Finds

Tumor cells usually rely on glucose to grow, but some are known to change their metabolism to survive in stressful environmental conditions. Researchers have discovered that is true in colorectal cancer, ... Read more

January 12, 2017

Asana Initiates Phase 1 Trial of New Therapy for Colorectal, Other Solid Tumors

Asana BioSciences is enrolling participants for a Phase 1 clinical trial assessing the safety, tolerability, and effectiveness of AS003 in patients with advanced solid tumors with the BRAF V600 mutation or with ... Read more

January 10, 2017

MMP9 Protein May Protect Against Inflammation-Derived Colon Cancer

An inflammatory protein called MMP9 may protect against the development of colitis-associated cancer (CAC), a type of colorectal cancer associated with chronic inflammatory diseases, a new study says. The study, ... Read more

January 5, 2017

Phase 1b Study of Combo Therapy for Metastatic Colorectal Cancer Begins Dosing

OncoMed Pharmaceuticals announced the dosing of the first patient in a Phase 1b clinical study evaluating the combination of its anti-DLL4 /VEGF bispecific antibody (OMP-305B83) and chemotherapy in people with second-line metastatic colorectal cancer ... Read more

January 3, 2017

Sensor Protein Seen to Protect Against Colon Cancer Development

Results from a new study suggest that a sensor protein called NLRC3 could play an important role in preventing the development of colon cancer. The study, “NLRC3 Is An Inhibitory Sensor ... Read more

December 22, 2016

Multi-Gene Screening Essential for Early Onset Colorectal Cancer Patients, Study Advises

Sixteen percent of colorectal cancer patients diagnosed before they are 50 years old have at least one inherited genetic mutation that increases their risk of developing the disease, according to ... Read more

December 20, 2016

Aspirin Slows Colon, Pancreatic Cancer Growth by Inhibiting Platelets, Study Shows

Aspirin may help slow the growth of localized colon and pancreatic cancers by inhibiting the cross-talk between cancer cells and platelets, according to research published in the American Journal of Physiology – ... Read more

December 15, 2016December 15, 2016

Notch Signaling Inhibitor Shows Promise as Treatment for Colon, Other Cancers, Study Shows

A new treatment for colon and other cancers that addresses mutations of the Notch signaling pathway is showing promise, researchers say. “Notch signalling is an important contributor to the development of ... Read more

December 13, 2016

Vaccine Being Developed May Help Prevent Colon Cancer Metastasis

Scientists at Thomas Jefferson University’s Sidney Kimmel Medical College in Philadelphia have developed an innovative new vaccine designed to halt the spread (metastases) of gastrointestinal tract cancers. These include malignancies ... Read more

Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research