June 8, 2017August 24, 2022
Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

The MEK inhibitor Mekinist (trametinib) is to be tested in combination with Opdivo (nivolumab) — or Opdivo plus Yervoy (ipilimumab) — in colorectal cancer ... Read more
June 6, 2017
Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Certain patients who underwent surgery for lymph-node positive colon cancer (stage 3) may require only three months of chemotherapy after surgery ... Read more
June 1, 2017June 1, 2017
Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

The MEK inhibitor binimetinib will soon be tested in combination with Opdivo (nivolumab) plus Yervoy (ipilimumab) in colorectal cancer patients ... Read more
May 30, 2017
PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

Trovagene’s PCM-075 therapy for several blood cancers and solid tumors, including colon cancer, proved safe in a Phase 1 clinical ... Read more
May 25, 2017May 25, 2017
FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Colorectal cancer patients with unresectable or metastatic tumors bearing a genetic feature — microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) — ... Read more
May 23, 2017
Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Overweight boys have a higher risk of developing colon cancer in adulthood, but if they lose the extra pounds by ... Read more
May 18, 2017May 18, 2017
Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Tom Marsilje, who survived stage IV colorectal cancer (CRC), has joined forces with New York-based Fight Colorectal Cancer to help patients search for ... Read more
May 16, 2017
Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

The Colon Cancer Coalition, a nonprofit organization that encourages grassroots efforts to promote colon cancer awareness and screening, is partnering ... Read more
May 11, 2017
Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

A new European project aims to develop an innovative endoscope device that can detect and diagnose colorectal cancer in its early ... Read more
May 9, 2017
Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

People who eat healthy, exercise, and do not smoke are less likely to report a personal history of colorectal cancer ... Read more
May 4, 2017May 4, 2017
RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

Small molecule compounds known as RLR agonists, being developed by Kineta to treat colon cancer, were seen to kill cancer ... Read more
May 2, 2017May 2, 2017
New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research

MIT researchers using the CRISPR-Cas9 genome editing and organoid technology have developed a new mouse model with a cancer that ... Read more

Colorectal Cancer Drug Significantly Improves Overall Survival

Eli Lilly and Company has announced that the RAISE trial, a Phase III study of ramucirumab (CYRAMZA™) in combination with chemotherapy in patients with metastatic colorectal cancer (mCRC), met its ... Read more

September 15, 2014September 15, 2014

Genomic Health’s Oncotype DX Colon Cancer Test Proven Cost-Effective by Mayo Clinic Study

Genomic Health, a provider of genomic-based diagnostic tests for treatment of early stage cancer, revealed positive results of a health economic study that demonstrates the direct reduction of medical costs and improvement of ... Read more

September 12, 2014September 12, 2014

XBiotech Halts Fast-Track Antibody Cancer Therapy Study; Reports Positive Phase III Results

Austin, Texas based biotechnology firm XBiotech U.S.A. Inc. has announced interim results from its fast-tracked Phase III study being conducted in the US for its anti-cancer agent Xilonix. A True ... Read more

September 11, 2014September 11, 2014

Study Analyzes Spatial Variation of Cancer in the Gut

Even though the small intestine has a greater cell mass than the colon, it is longer, has a greater surface area and a faster rate of epithelial turnover, the incidence ... Read more

September 11, 2014September 11, 2014

Task Force Recommends Newly Diagnosed Colorectal Cancer Patients Get Genetic Tumor Tests

Newly diagnosed colorectal cancer patients are recommended to partake in genetic testing of their tumors by the U.S. Multi-Society Task Force on Colorectal Cancer, which recently compiled a new guideline for ... Read more

September 9, 2014September 9, 2014

Immunotoxins May Be Useful As a Colon Cancer Therapy

Immunotoxins, antibodies targeted towards deadly toxins, have been a central focus of research to find immunotherapies for cancer. However, results have been disappointing so far, partly because cancer and normal ... Read more

September 8, 2014September 8, 2014

Researchers Developing New User-Friendly Colorectal Cancer Test

Researchers from McMaster University in Hamilton, Canada, are developing a simple, non-invasive test for colorectal cancer, to ultimately increase the number of people screened for this type of cancer. “I ... Read more

September 5, 2014September 5, 2014

Prediction Model Estimates Time of Colorectal Cancer Patient Survival

“How long do I have, doctor?” is a question on the minds of many patients diagnosed with metastatic colorectal cancer. In light of a new study published in Annals of Oncology entitled ... Read more

September 4, 2014September 4, 2014

APC Protein Plays Role in Suppressing Colorectal Cancer, According to Study

Researchers from the University of Kansas have uncovered a new role for the protein adenomatous polyposis coli (APC) in suppressing colorectal cancer (CRC). Functional loss of the APC protein is thought ... Read more

September 3, 2014September 3, 2014

Vaccinogen’s OncoVAX Enters Phase IIIb Clinical Trial for Stage 2 Colon Cancer

Vaccinogen, a cancer vaccine company, will begin ACTIVE, a confirmatory Phase IIIb pivotal study of the company’s vaccine OncoVax ®, in patients with resectable Stage 2 colon cancer, under a U.S. Food ... Read more

September 2, 2014September 2, 2014

DNA-based Noninvasive Colorectal Cancer Screening Test Approved by FDA

Texas based Exact Sciences Corp. announced that the U.S. Food and Drug Administration (FDA) has approved Cologuard, the company’s noninvasive, stool DNA colorectal cancer screening test. Furthermore, it also received a proposed coverage memorandum ... Read more

August 29, 2014August 30, 2014

Experimental Therapy Showing Promise in Studies For Subset of Stage III Colon Cancer Patients

Researchers from the University of Washington have found that irinotecan-based therapy, a topoisomerase 1 inhibitor, can improve survival rates in a subset of patients with stage III colon cancer. In ... Read more

Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research