June 8, 2017August 24, 2022
Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

The MEK inhibitor Mekinist (trametinib) is to be tested in combination with Opdivo (nivolumab) — or Opdivo plus Yervoy (ipilimumab) — in colorectal cancer ... Read more
June 6, 2017
Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Certain patients who underwent surgery for lymph-node positive colon cancer (stage 3) may require only three months of chemotherapy after surgery ... Read more
June 1, 2017June 1, 2017
Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

The MEK inhibitor binimetinib will soon be tested in combination with Opdivo (nivolumab) plus Yervoy (ipilimumab) in colorectal cancer patients ... Read more
May 30, 2017
PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

Trovagene’s PCM-075 therapy for several blood cancers and solid tumors, including colon cancer, proved safe in a Phase 1 clinical ... Read more
May 25, 2017May 25, 2017
FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Colorectal cancer patients with unresectable or metastatic tumors bearing a genetic feature — microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) — ... Read more
May 23, 2017
Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Overweight boys have a higher risk of developing colon cancer in adulthood, but if they lose the extra pounds by ... Read more
May 18, 2017May 18, 2017
Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Tom Marsilje, who survived stage IV colorectal cancer (CRC), has joined forces with New York-based Fight Colorectal Cancer to help patients search for ... Read more
May 16, 2017
Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

The Colon Cancer Coalition, a nonprofit organization that encourages grassroots efforts to promote colon cancer awareness and screening, is partnering ... Read more
May 11, 2017
Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

A new European project aims to develop an innovative endoscope device that can detect and diagnose colorectal cancer in its early ... Read more
May 9, 2017
Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

People who eat healthy, exercise, and do not smoke are less likely to report a personal history of colorectal cancer ... Read more
May 4, 2017May 4, 2017
RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

Small molecule compounds known as RLR agonists, being developed by Kineta to treat colon cancer, were seen to kill cancer ... Read more
May 2, 2017May 2, 2017
New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research

MIT researchers using the CRISPR-Cas9 genome editing and organoid technology have developed a new mouse model with a cancer that ... Read more

November 5, 2014November 5, 2014

Study Finds NSAIDs Can Prevent Colon Cancer

A recent study published in the Proceedings of the National Academy of Sciences, titled “BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal anti-inflammatory drugs”, has ... Read more

November 4, 2014November 4, 2014

Study Shows S-1 Adjuvant Chemotherapy Efficiency in Colon Cancer Treatment

In a recent study titled “S-1 as adjuvant chemotherapy for stage III colon cancer: a randomized phase III study (ACTS-CC trial)”, published in the Annals of Oncology, Dr. Yoshida and colleagues at the Cancer Chemotherapy Center, Osaka Medical College Hospital, Osaka, Japan, designed a ... Read more

November 3, 2014

New Data Supports Efficacy of Fuse Endoscopy System In Colorectal Cancer Diagnosis

EndoChoice, a company focusing on manufacturing specialized endoscopic imaging, has announced its latest study results confirming the efficacy of the Fuse Full Spectrum Endoscopy System at the American College of ... Read more

October 31, 2014October 31, 2014

Study Finds Protein Complex Slows Colon Cancer Tumor Growth

In a recent study titled “A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth” published in the Molecular Cell journal, ... Read more

October 30, 2014October 30, 2014

Study Finds Mutation In Colorectal Cancers May Increase Susceptibility to New Cancer Drugs

A study titled “RNF43 is frequently mutated in colorectal and endometrial cancers” and published in Nature Genetics found a new gene, RNF43 that is frequently mutated in colorectal adenocarcinomas and ... Read more

October 29, 2014

Study Finds Sphingolipids As Key Link Between Diet, Inflammation And Cancer

In a recent study titled “Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs”, published in The Journal of Clinical Investigation, a team of researchers from the Children’s Hospital Oakland ... Read more

October 28, 2014October 28, 2014

Colon Cancer Patients May Benefit From Prehabilitation Before Surgery

A new study entitled “Prehabilitation versus Rehabilitation: A Randomized Control Trial in Patients Undergoing Colorectal Resection for Cancer” suggests that a prehabilitition program including exercise, healthy diet and relaxation techniques ... Read more

October 27, 2014October 27, 2014

Study Finds Mechanism Involved in Diagnosis And Targeted Therapy of Colorectal Cancer

In a recent study published in Cancer Cell titled “Rab1A Is an mTORC1 Activator and a Colorectal Oncogene”, a team of researchers from the Rutgers Cancer Institute, New Jersey, has ... Read more

October 24, 2014October 24, 2014

Taiho’s Investigational Colorectal Cancer Drug Receives FDA Fast Track Designation

The U.S. Food and Drug Administration (FDA) has granted Fast Track designation for Taiho Oncology’s TAS-102 (trifluridine/tipiracil hydrochloride) for the treatment of refractory metastatic colorectal cancer (mCRC). The Fast Track ... Read more

October 23, 2014October 23, 2014

Phase 3 Study on Metastatic Colorectal Cancer Enrolls First Patient

A new global Phase 3 clinical study to treat patients with metastatic colorectal cancer (mCRC), has enrolled its first patient, as announced Boehringer Ingelheim Pharmaceuticals Inc. (BI). Colorectal cancer is the third ... Read more

October 23, 2014October 23, 2014

Genetic Tests in Population Leave Colorectal Cancer Screening Rates Unchanged

An “excellent” study–defined as such by meeting the randomized controlled trial requirement of Level I Evidence in medicine–from the Fox Chase Cancer Center and Jefferson Medical College in Pennsylvania and ... Read more

October 21, 2014October 21, 2014

Oratecan Shows Promise in Phase I Clinical Trial for Colon Cancer

Hanmi Pharmaceuticals and Kinex Pharmaceuticals recently announced preliminary findings from a Phase I clinical trial of Oratecan, an oral formulation of irinotecan (Camptosar), an already-approved intravenous treatment for colon cancer. The oral ... Read more

Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research