June 8, 2017June 8, 2017
Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

The MEK inhibitor Mekinist (trametinib) is to be tested in combination with Opdivo (nivolumab) — or Opdivo plus Yervoy (ipilimumab) — in colorectal ... Read more
June 6, 2017
Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Certain patients who underwent surgery for lymph-node positive colon cancer (stage 3) may require only three months of chemotherapy after ... Read more
June 1, 2017June 1, 2017
Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

The MEK inhibitor binimetinib will soon be tested in combination with Opdivo (nivolumab) plus Yervoy (ipilimumab) in colorectal cancer ... Read more
May 30, 2017
PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

Trovagene’s PCM-075 therapy for several blood cancers and solid tumors, including colon cancer, proved safe in a Phase 1 ... Read more
May 25, 2017May 25, 2017
FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Colorectal cancer patients with unresectable or metastatic tumors bearing a genetic feature — microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) ... Read more
May 23, 2017
Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Overweight boys have a higher risk of developing colon cancer in adulthood, but if they lose the extra pounds ... Read more
May 18, 2017May 18, 2017
Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Tom Marsilje, who survived stage IV colorectal cancer (CRC), has joined forces with New York-based Fight Colorectal Cancer to help patients search ... Read more
May 16, 2017
Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

The Colon Cancer Coalition, a nonprofit organization that encourages grassroots efforts to promote colon cancer awareness and screening, is ... Read more
May 11, 2017
Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

A new European project aims to develop an innovative endoscope device that can detect and diagnose colorectal cancer in its ... Read more
May 9, 2017
Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

People who eat healthy, exercise, and do not smoke are less likely to report a personal history of colorectal ... Read more
May 4, 2017May 4, 2017
RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

Small molecule compounds known as RLR agonists, being developed by Kineta to treat colon cancer, were seen to kill ... Read more
May 2, 2017May 2, 2017
New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research

MIT researchers using the CRISPR-Cas9 genome editing and organoid technology have developed a new mouse model with a cancer ... Read more

More Than Nine-month Delay Between Feces Test and Colonoscopy Increases Colon Cancer Risk

Failing to get a diagnostic colonoscopy within nine months of a feces test that indicates the possibility of colorectal cancer increases the risk of a person developing the cancer, a ... Read more

April 20, 2017April 20, 2017

Colon Cancer Experimental Therapy AMC303 Also Inhibits Pancreatic Tumors in Mice, Study Shows

AMC303 inhibited tumor growth and prevented the spread of colorectal, and other cancer cells, and of a pancreatic cancer in a mouse model, amcure reported at the American Association for Cancer Research’s ... Read more

April 18, 2017April 18, 2017

UConn Center Uses More than Colonoscopy to Prevent Colorectal Cancer

While regular colonoscopy remains the gold standard in preventing colorectal cancer, the understanding of how this cancer and the polyps that come before it develop is changing rapidly. Joel Levine, ... Read more

April 13, 2017

FDA Grants Priority Review to Application Seeking Opdivo’s Approval for Certain Colorectal Cancer Patients

The supplemental Biologics License Application (sBLA) requesting the extension of Opdivo’s indications to include metastatic colorectal cancer patients who have mismatch repair deficiencies (dMMR) or high microsatellite instability (MSI-H), ... Read more

April 6, 2017

Patient Is Key Factor That Predicts Colorectal Cancer Screening, Study Finds

The term “self-efficacy,” or a patient’s confidence to schedule, plan for, and complete their part in medical screening procedures, was found to be a key determining factor for predicting ... Read more

March 30, 2017March 30, 2017

Disabled Adults Less Likely to Receive Routine Colorectal Cancer Screening, Study Finds

Americans with impaired vision, intellectual disabilities or spinal cord injuries are less likely to receive recommended colon cancer screenings than the general population, a new study found. The study, “Colorectal ... Read more

March 29, 2017

Biobank Can Help Colon Cancer Patients Manage Their Disease Better

One way for those with colorectal cancer to become more involved in the management and treatment of their disease is to check out the Penn State Colorectal Diseases Biobank. ... Read more

March 23, 2017March 23, 2017

Gut Bacteria Explains Increased Colon Cancer Risk in African-Americans

The higher intake of animal fat and meat among African-Americans is a potential environmental risk factor for colorectal cancer, as it changes to composition of their gut microbiota, according to ... Read more

March 21, 2017March 21, 2017

Enhancer DNA Regions May Promote Colon Cancer Growth

Colon cancer growth may be dependent on increased activity in enhancer DNA regions, which act to trigger the harmful actions of known cancer genes, according to a study that ... Read more

March 16, 2017March 16, 2017

Quantifying Immune Cells in Colon Tumors May Identify Cancer Patients at High Risk of Recurrence

The presence of immune cells within tumors can predict how well cancer patients are likely to fare, according to a recent study. Researchers at New Zealand’s University of Otagov found ... Read more

March 14, 2017

Healthy Lifestyle Overrides Genetic Risk Factors of Colon Cancer

Lifestyle factors play a much larger role than genetic risk in determining who gets colon and rectal cancer, according to a study that modeled cancer risk using both lifestyle ... Read more

Clinical Trial to Test Mekinist as Combo Therapy in Advanced Colorectal Cancer Patients

Certain Colon Cancer Patients May Need a Shorter Chemotherapy Course, International Study Finds

Binimetinib Triple Combo to Be Tested in Microsatellite Stable Colorectal Cancer Patients

PCM-075 Proves Safe as Treatment for Colon, Other Cancer Types, Phase 1 Trial Shows

FDA Approves Merck’s Keytruda for Colorectal, Other Solid Cancers with Specific Genetic Feature

Increased Colon Cancer Risk in Overweight Boys Reversed by Slimming Down, Danish Study Finds

Stage IV Colorectal Cancer Survivor Updates Microsatellite Stable CRC Clinical Trial Finder

Colon Cancer Coalition Partnering with Olympus to Try to Increase the Disease’s US Screening Rate

Researchers Take Aim at Early-stage Colon Cancer by Working on New Endoscope Device

Online Survey Shows What Lifestyle Changes People Can Make to Reduce Risk of Colon Cancer

RLR Agonists Seen to Promote Immune Response Against Colon Cancer Cells in Early Study

New MIT Mouse Model Using CRISPR Technology Could Speed Up Colon Cancer Research